摘要
烟草作为一种重要的经济作物仍在世界各地广泛种植。阐明烟草的化学成分及生物活性将为后续研究烟草植物提供有益线索。在查询、研究了国内外相关文献的基础上,本文分析、总结了近三十年（1987-2016）烟草化学成分及其生物活性研究成果。烟草非挥发性成分主要有二萜、倍半萜、黄酮和生物碱,近三十年新报道的烟草化学成分几乎全为二萜和倍半萜。其化学成分的生物活性主要表现在生物碱、二萜、倍半萜成分等抗神经系统疾病方面（如抗阿尔茨海默症和影响情绪及睡眠）、抗肿瘤、抗乙型肝炎病毒（HBV）和抗菌方面。
Nicotiana tabacum as an important economic crop was widely grown in world. Investigating its chemical constituents and their bioactivities was Very important to provide valuable clues for future research about N. tabacum. In this study,we analyzed and summarized the progress of research on chemical constituents and bioactivities of N. tabacum from 1987 to 2016 on the basis of reviewing the related papers of domestic and overseas. Diterpenoids, sesquiterpoids, flavonoids and alkaloids were the main constituents for its non-volatile components. Almost all compounds isolated from N. tabacum during 1987 to 2016 were diterpenoids and sesquiterpoids. Among those compounds of tobacco, mainly activities were diterpenoids, sesquiterpoids and alkaloids,etc, and their activities basically possessed the neuroprotective effect against the nerve damage （anti-Alzheimer＇s disease, affect mood and sleep）, anti-tumor, anti-HBV and anti-bacterial activities.
出处
《天然产物研究与开发》
CAS
CSCD
北大核心
2016年第10期1657-1663,1621,共8页
Natural Product Research and Development
基金
广西高校科学技术研究项目重点项目(KY2015Z D095)
右江民族医学院博士引进科研启动课题(2014-2)
关键词
化学成分
生物活性
烟草
chemical constituent
bioactivity
Nicotiana tabacum
