江西省进贤县4515例居民骨密度流行病学调查分析

Epidemiological study of bone mineral density in 4515 residents in Jinxian Area of Jiangxi

目的调查江西省进贤县4515例居民的骨密度情况及骨质疏松症(OP)患病情况,为OP的诊断和防治提供基础资料。方法采用UBS-3000plus全自动定量超声骨密度测量系统对江西省进贤县4515例居民进行桡骨定量超声检测和分析。结果⑴无论男性或女性桡骨超声速率(SOS)峰值出现在30岁之前,30岁以后骨密度逐渐下降,各年龄段差异具有统计学意义(P<0.05)。⑵男性与女性骨质疏松症患病率分别为16.1%和20.8%,差异有统计学意义(P<0.01);30岁以后各年龄段女性OP患病率明显高于男性(P<0.01)。⑶Pearson相关分析显示峰值骨量后,OP患病率与年龄呈明显正相关。结论江西省进贤县居民中骨密度异常者所占比率较高,且女性骨质疏松的患病率高于男性,尤其是中老年女性是骨质疏松的高发人群;早期进行骨密度筛查,是预防骨质疏松的有效措施。定量超声检测骨密度简便易行,适用于早期骨密度筛查。

Objective To explore the changes of bone mineral density（BMD） in 4515 residents in Jinxian Area of Jiangxi and the incidence of osteoporosis,and to provide basic information and basis for the diagnosis and prevention of osteoporosis.Methods Quantitative bone mass of 4515 healthy subjects was measured and analyzed using quantitative ultrasound bone densitometry.Results ⑴No matter men or women,the peak of speed of sound（SOS） of the radius appeared at the age before 30 years old,with a trend of descending after 30 years old.All ages are statistically significant differences（P〈0.05）.⑵The prevalence of OP was 16.1%in men and 20.8% in women.The prevalence in women was significantly higher than that in men（P〈0.01）.In addition,the prevalence of osteoporosis in women at different ages was still significantly higher than that in men after 30 years old（P〈0.0l）.⑶ Pearson correlation analysis indicated that the incidence of osteoporosis was positively related to the age after the peak bone mass.Conclusion People with abnormal bone mineral density demonstrates a high proportion in residents in Jinxian Area of Jiangxi.Meanwhile,the bone mass of middle-aged and old women decreases obviously,and the incidence of OP is significantly higher than that in men with the same age.Early screening for bone mineral density is an effective measure to prevent OP.Quantitative ultrasound is easy to operate,could be used to early screening.