CRP、GLU、TG和AMS在急性胰腺炎诊断中的价值

Clinical value of CRP, GLU, TG and AMS in the diagnosis of acute pancreatitis

目的探讨C反应蛋白(CRP)、血糖(GLU)、三酰甘油(TG)及淀粉酶(AMS)对急性胰腺炎的临床诊断价值。方法选取120例急性胰腺炎(AP)患者为研究对象,其中重症急性胰腺炎组(SAP)52例,轻症急性胰腺炎组(MAP)68例。选择同期的180名健康人作为对照组,对比各组患者发病后第1、3、5天时外周血内CRP、GLU、TG、AMS水平、症状持续时间。结果发病后第1、3、5天时,CRP、GLU、TG、AMS水平从高到低依次为SAP组、MAP组、健康对照组。SAP组患者症状持续时间均高于MAP组,且差异有统计学意义(P<0.05)。血清CRP、GLU、TG、AMS水平与腹痛、高热、呕吐的持续时间均呈正相关。结论血清CRP、GLU、TG水平与AP的症状持续时间及病情密切相关,可作为SAP诊治的重要临床依据。

Objective To investigate the clinical value of combined detection of C reactive protein （CRP）, blood glucose （GLU）, triglyceride （TG） and amylase （AMS） for the patients with acute pancreatitis. Methods 120 patients were selected for study, 52 cases of severe acute pancreatitis group （SAP） and 68 cases of mild acute pancreatitis group （MAP）, while 180 healthy persons were selected as the control group. The CRP, GLU, TG, AMS and the duration of symptom at 1 day, 3 days and 5 days after the onset of the disease were compared. Results At the 1 day, 3 days and 5 days after the onset of disease, the levels of CRP, GLU, TG and AMS of the SAP group〉MAP group〉control group. The duration of symptoms in SAP group was higher than that of MAP group, and the difference was statistically significant （P〈0.05）. The levels of serum CRP, GLU, TG and AMS were positively correlated with the duration of abdominal pain, fever and vomiting. Conclusion The levels of serum CRP, GLU and TG were closely related to the duration and severity of AP, and could regarded as an important clinical basis for the diagnosis and treatment of SAP.