应用VENUS-A瓣膜完成经导管主动脉瓣植入术的经验总结

Experience of transcatheter aortic valve implantation with VENUS-A valve

目的总结应用国产VENUS-A瓣膜完成经导管主动脉瓣植入术(transcatheter aortic valve implantation,TAVI)的经验。方法随访观察广东省人民医院2例应用VENUS-A瓣膜完成TAVI手术患者的瓣膜和心脏功能的变化,以及术后30 d的病死率和主要并发症。结果总共有2例患者经股动脉完成手术,分别是66岁和74岁,纽约心脏协会心功能均为3级,美国外科医师协会评分(STS)分别为2分和11分。两例患者均顺利完成手术,术后30 d没有死亡和严重并发症。术后心功能明显改善。结论使用国产VENUS-A瓣膜完成TAVI手术是有效和安全的,但还需要进一步的验证。

Objectives To summary the experience of transeatheter aortic valve implantation （TAVI） with VENUS-A valve in China. Methods Two patients underwent TAVI with VENUS-A valve in Guangdong General Hospital. The improvements of valve and heart function were evaluated as well as 30-day mortality and major complications. Results Two TAVI procedures with VENUS-A valve were performed in our hospital, of whieh all were transfemoral. Age of the 2 patients were 66 years old and 74 years old, New York Heart Association heart functions were both 3 degree, and the Society of Thoracic Surgeons scores were 2 and 11. TAVI was successfully conducted in the two patients. There was no second valve implantation. Moreover, no 30-day mortality or eomplieations was reported, and the heart and valve funetions had improved significantly. Conclusions This early experienee has provided preliminary evidence for the safety and efficacy of TAVI procedure with VENUS-A valve in the developing world.