海藻酸钠-壳聚糖-五倍子提取物微胶囊琼脂平皿扩散法抗菌性研究

The Evaluation of the Antibacterial Properties of Natural Gallnut Extract/Sodium Alginate/Chitosan Microcapsules by the Agar Plate Diffusion Method

本文采用锐孔造粒法,以海藻酸钠、壳聚糖为壁材,五倍子提取物为芯材制备了海藻酸钠-壳聚糖-五倍子提取物微胶囊。利用扫描电镜、红外光测试等手段确定了制备此微胶囊的最佳工艺,并采用琼脂平皿扩散法测定及评价了所制备微胶囊的抑菌性能。实验结果表明：制得的微胶囊包封效果、成球性和粒径均一性良好,且具有较好的抑菌性能,抑菌效果理想。

By using orifice granulation method, microcapsules with sodium alginate and chitosan as the wall materials and gallnut extract as the core material are prepared. Scanning electron microscope and infrared test method are adopted to determine the best process for preparing the microcapsules, and the agar plate diffusion method is applied in the measurement trod evaluation of the antibacterial properties of the prepared microcapsules. The test results show that the prepared microcapsules have good encapsulation effect, pelletizing properties and particle size uniformity. They also have good antibacterial properties, which can achieve ideal antibacterial effect.