归脾汤治疗50例上消化道出血合并急性冠脉综合征的临床观察

Clinical Observation of Gastrointestinal Bleeding Associated with Acute Coronary Syndrome on 50 Cases of Spleen Treated

目的:观察上消化道出血合并急性急性冠状动脉综合征(冠脉综合征)患者的临床特点、探寻中西医结合的治疗方案。方法:将100例临床诊断为上消化道出血的患者随机分为治疗组和对照组,每组各50例。治疗组给予中药归脾汤联合西药治疗,对照组仅给予西药治疗,疗程均为2周,观察两组临床疗效、症状积分变化及血红蛋白水平的变化。结果:治疗组患者总有效率为86%显著优于对照组80%,差异有显著性(P<0.05)。治疗组症状积分等指标改善方面均明显优于对照组(P<0.05)。治疗后治疗组患者血清Hg B高于对照组,有统计学意义(P<0.05);治疗后治疗组患者的CK、CK-MB水平显著低于对照组,有统计学意义(P<0.05)。结论:归脾汤联合西药治疗上消化道出血合并急性冠脉综合征疗效显著,能明显地改善患者的临床症状及实验室指标;其作用机制可能与中药的益气健脾养血、从而能促血红蛋白的生成有关。

Objective： To observe the 30 patients with gastrointestinal hemorrhage clinical characteristics of patients withacute coronary syndrome,explore integrative medicine treatment options.Methods：The clinical diagnosis of 100 cases of uppergastrointestinal bleeding in patients were randomly divided into treatment group and control group, n = 50.The treatment groupreceived traditional Chinese medicine spleen soup combined with western medicine,western medicine control group only receivedtreatment, a course of two weeks, observe the changes in clinical efficacy, symptom score changes and hemoglobin levels.Results：In patients treated with total effective rate of 86% was significantly better than the control group to 80%, the differencewas statistically significant （P〈0.05）. Indicators to improve the treatment group symptom score and so on were significantlybetter than the control group （P〈0.05）. After treatment, patients treated with serum HgB higher, statistically significant （P〈0.05）; after treatment, patients treated with CK, CK-MB levels were significantly lower than the control group was statisticallysignificant （P〈0.05）. Conclusion： The spleen soup combined with western medicine on gastrointestinal hemorrhage with acutecoronary syndrome a significant effect, can significantly improve the clinical symptoms and laboratory parameters of patients; themechanism may Spleen Qi, nourishing and medicine, so that it can promote the formation of hemoglobin related.