熥络宝治疗AECOPD的临床疗效观察

Curative effect of Tongluobao in the auxiliary treatment of AECOPD

目的 探讨中药熥络宝理疗仪辅助治疗慢性阻塞性肺疾病急性加重期（AECOPD）的疗效.方法 选取AECOPD住院患者60例,采用随机数字表法将患者分为实验组和对照组,各30例;全部AECOPD患者均采用吸氧、化痰、平喘与抗炎等临床常规对症治疗措施,实验组在对照组基础上采用熥络宝治疗,疗程7d.比较两组治疗前后临床症状及体征（咳嗽、咳痰、呼吸困难、肺部啰音等的改善情况）、6 min行走距离（6-MWD）、肺通气功能.结果 实验组和对照组治疗有效率分别为90.0％、73.3％,前者明显高于后者（P＜0.05）;实验组和对照组患者治疗前6-MWD[（301.1±29.3）m vs.（301.5±29.6）m]、FVC[（2.29±0.30）L vs.（2.23±o.21）L]、FEV1[（1.16±0.16）L vs.（1.15±0.12）L]比较差异无统计学意义（P＞ 0.05）;治疗后实验组和对照组患者6-MWD[（331.4±34.2）m vs.（308.0±29.9）m]、FVC[（2.51±0.28）L vs.（2.36±0.18）L]、FEV1[（1.52±0.28）L vs.（1.22±0.07）L]均较治疗前提高,且实验组显著高于对照组（P＜0.05）.结论 中药熥络宝理疗仪在辅助治疗AECOPD患者中疗效显著,安全性高,值得临床推广.

Objective To discuss the curative effect of Chinese medicine Tongluobao physiotherapy instrument in the auxiliary treatment of acute exacerbation of chronic obstructive pulmonary disease （AECOPD）.Methods 60 patients with AECOPD were selected and divided into experimental group and control group according to the random number table,30 cases in each group.All patients underwent routine clinical symptomatic treatment measures such as oxygen inhalation,eliminating phlegm,relieving asthma,and anti-inflammation;experimental group was given Tongluobao treatment on the basis of control group,the course of 7 d.Compared clinical symptoms and physical signs （cough,sputum,dyspnea,pulmonary rale） of two groups before and after treatment,6 minutes walking distance （6-MWD）,pulmonary ventilation function.Results The treatment efficiency of experimental group and control group were 90.0% and 73.3% （P〈0.05）.There were no statistically significant differences in 6-MWD,FVC,FEV1 between experimental group and control group before treatment [（301.1±29.3）m vs.（301.5±29.6）m,（2.29±0.30）L vs.（2.23±0.21）L,（1.16±0.16）L vs.（1.15±0.12）L;P〉0.05],6-MWD,FVC,FEV1 in experimental group after treatment were significantly higher than those in control group [（331.4±34.2）m vs.（308.0±29.9）m,（2.51 ±0.28）L vs.（2.36±0.18）L,（1.52±0.28）L vs.（1.22±0.07）L;P〈0.05].Conclusion Chinese medicine Tongluobao physiotherapy instrument in the auxiliary treatment of AECOPD has distinct curative effect,high safety,worthy of further clinical promotion.