酮咯酸氨丁三醇对腹部手术患者术后疼痛、躁动及基础体征的改善效果

The effect of ketorolac tromethamine in improving postoperative pain, restlessness, and basic signs of patients with abdominal operation

目的 研究酮咯酸氨丁三醇对腹部手术患者术后疼痛、躁动及基础体征的改善效果.方法 选择2014年6月至2015年6月我院80例腹部手术患者作为研究对象,采用随机数表法分为两组,每组40例.对照组给予常规麻醉,观察组在常规麻醉基础上加用酮咯酸氨丁三醇.比较两种方法对患者术后疼痛、躁动及基础体征的影响.结果 观察组手术结束后2h （T2）、手术结束后12 h（T3）及手术结束后24 h（T4）VAS评分分别为（1.24±0.23）、（1.21±0.17）及（1.19±0.30）,均显著低于对照组,差异有统计学意义（P＜ 0.05）.观察组术后躁动发生率为42.5％,显著低于对照组的65％,差异有统计学意义（P＜0.05）.观察组手术结束时（T1）、T2、T3及T4时血压、心率及血氧饱和度等基础生命体征比较,差异均无统计学意义（P＞0.05）.结论 酮咯酸氨丁三醇能显著减轻患者术后疼痛,有利于改善患者术后躁动状态,维持生命体征的稳定.

Objective To study the effect of ketorolac tromethamine in improving postoperative pain,restlessness,and basic signs of patients with abdominal operation.Methods 80 patients underwent abdominal surgery in our hospital from June 2014 to June 2015 were selected as the research object,and divided into two groups with the random number table method,40 cases in each group.Control group was given routine anesthesia,and observation group was given ketorolac tromethamine on the basis of routine anesthesia.Compared the effect on postoperative pain,restlessness,and basic signs of two methods.Results VAS score in observation group 2 h after the end of the operation （T2）,12 h after the end of the operation （T3）,24 h after the end of the operation （T4） were （1.24±0.23）,（1.21±0.17）,（1.19±0.30） respectively,significantly lower than those in control group,with statistically significant differences （P〈0.05）.The incidence of postoperative restlessness in observation group was 42.5%,significantly lower than that in control group （65%）,with statistically significant difference （P〈0.05）.There were no statistically significant differences in blood pressure,heart rate,and blood oxygen saturation in observation group at the end of the operation （T1）,T2,T3,T4 （P〉0.05）.Conclusion Ketorolac tromethamine can significantly reduce postoperative pain,improve postoperative restlessness after the operation,maintain vital signs stable.