早期经口进食在结直肠癌术后应用的研究进展

Research progress of early oral feeding in patients after colorectal cancer surgery

结直肠癌是目前第三大常见的恶性肿瘤，同时也是全球范围内主要的公众健康问题，手术切除是当前主要的治疗方法之一。术后能否早期经口进食（EOF）是当前主要的争论热点之一，传统观念认为结直肠癌根治术因为采用全身麻醉影响肠道运动，以及存在吻合口等因素，术后EOF可能会带来更多的并发症，因此大多数外科中心术后往往选择肠外营养，待肠道功能恢复后逐步恢复正常饮食。随着20世纪90年代末快速康复外科（FTS）理念的提出，EOF逐渐应用于临床。本文通过查阅国内外有关研究，结果证明术后EOF是安全有效的，不仅可以增强患者免疫力、降低术后并发症的发生率，还可以促进患者快速康复。

Colorectal cancer （CRC） is the third most common cancer in human and the major pub- lic health problems worldwide. Surgery is still the preferred treatment. The traditional notion holds that, be- cause of the anastomotic stoma and the affected intestinal motility after general anesthesia, early oral feeding （EOF） may bring many complications, so most surgery centers tend to choose parenteral nutrition rather than enteral nutrition until there exist a sign of the passage of flatus and bowel sounds. With the concept of fast track surgery occurring at the end of 1990s, EOF was gradually used in clinical. This review that sum- marizes the articles from domestic and overseas demonstrates that EOF is safe and efficient, and that it can strengthen the patients Smmunity, reduce the operative complications, and fasten the patients recovery.