摘要
以TEBA季铵盐为相转移催化剂,苯甲醛为原料合成苦杏仁酸是一种新的合成方法。新的合成方法加快了反应速度提高了收率,也简化了操作,代替了以往多由苯甲醛与氰化钠加成得氰醇再水解制得的传统方法,克服了路线长,操作不便,劳动保护要求高的缺点。介绍了实验条件对合成苦杏仁酸反应的具体影响,找到了合成实验的最佳条件。
Using TEBA quaternary ammonium salt as phase transfer catalyst,the synthesis of bitter almond acid by using phenyl formaldehyde as raw material is a new synthetic method.Greatly accelerate the reaction speed improve the yield,but also simplifies the operation,instead of the previous by benzaldehyde and sodium cyanide addition to cyanohydrin then hydrolyzing the long route, inconvenient operation,labor protection requirements of the shortcomings of high.The specific effects of the experimental conditions on the synthesis of bitter almond acid were introduced,and the optimum conditions for the synthesis of bitter almond were found.
出处
《化工设计通讯》
CAS
2016年第7期86-86,共1页
Chemical Engineering Design Communications
关键词
相转移催化
苯甲醛
苦杏仁酸
phase transfer catalysis
phenyl formaldehyde
bitter almond acid