索利那新治疗双"J"管置入后尿路感染症状的疗效观察

Solifenacin Succinate Tablets Treatment Curative Effect Observation of Symptoms of Urinary Tract Infection after the Double "J" Tube

目的:观察琥珀酸索利那新对经皮肾镜碎石取石术患者术后留置双"J"管期间发生泌尿系统感染的疗效。方法:回顾性分析133例成功行经皮肾镜碎石取石术并常规留置双"J"管的患者,随机分为治疗组(n=67)和对照组(n=66)。治疗组给予索利那新片治疗,对照组仅给予饮水、休息等常规治疗。所有患者在置管5周后(拔管前一天)均随访并完成血、尿常规检验。结果:治疗组血、尿常规白细胞计数均低于对照组,治疗组均较对照组的泌尿系统的感染发生率低(P<0.05)。结论:口服索利那新能有效降低泌尿系统感染的可能性,降低患者在置管期间出现尿频、尿急、血尿、腰部疼痛、发热等并发症的概率,提高患者的生活质量,值得临床推广应用。

Objective： To observe the curative effect of the indwelling double ＂J＂ tube on the treatment of urinary tract infection in patients with percutaneous renal stone. Methods： A retrospective analysis of 133 cases who had taken the successful percutaneous lithotripsy and double ＂J＂ tube was conducted and the patients were randomly divided into the treatment group（n=67） and the control group（n=66）. The patients in the treatment group were treated with the solifenacin succinate tablets, while the patients in the control group were treated with the regular methods, which including enough water and rest. Then the blood and urine examination were done after the treatment for five weeks. Results： The blood and urine leukocyte counts in the treatment group were lower than those of the control group, and the incidence of urinary infection in the treatment group was lower than that of the control group, and the differences were statistically significant（P〈0.05）. Conclusions： Solifenacin succinate tablets can reduce the possibility of urinary tract infections,which can reduce the urgency, hematuria, flank pain, and fever, and improve the patient’s quality of life, which is worth of clinical application.