不同体位对严重肥胖者血氧饱和度的影响

Effect of Different Position on the Oxygen Saturation of Patients with Severe Obesity

目的:探讨不同体位对严重肥胖者血氧饱和度的影响。方法:16名平均体重指数(BMI)为40±5肥胖者和16名年龄匹配的正常体重者被纳入研究。分别在不同体外下(坐位、仰卧位、侧卧位)对所有参与者进行动脉血气监测。结果:肥胖者于坐位时动脉Pa O_2为75±4 mm Hg,Pa CO_2为37±3 mm Hg;仰卧位时动脉Pa O_2为62±5 mm Hg,Pa CO_2为47±5 mm Hg;侧卧位时Pa O_2为73±3 mm Hg,Pa CO_2为39±2 mm Hg;而正常体重者无明显变化。结论:严重肥胖者于平卧位时更容易出现低氧及高碳酸血症。

Objective： To investigate the effect of different positions on the oxygen saturation in subjects with severe obesity. Methods： Eight obese subjects （OS） with a mean body mass index （BMI） of 40± 5 kg/m^2 and Eight age-matched normal-weight control subjects （CS） were enrolled in the study. Under different positions （sitting, supine and lateral positions ）, all participants arterial blood gas were be monitored. Results： Obese subjects when supine had a significantly less value of PaO2 and a more severe hypercapnia. In sitting postures, PaO2 was 75 ± 4 mmHg, PaCe2 was 37 ±3 mmHg; In supine postures, PaO2 was 62± 5 mmHg, PaCe2 was 47 ± 5 mmHg; In lateral postures, PaO2 was 73±3 mmHg, PaCe2 was 39 ± 2 mmHg; while no significant changes in the normal weight. Conclusion： Patients with severe obesity were more prone to have hypoxia and hypercapnia in the supine position.