DTI研究脑白质疏松症对皮质脊髓束的影响

Impact of leukoaraiosis on corticospinal tract by DTI study

目的探讨DTI技术用于观察不同Mantyla分级脑白质疏松症患者皮质脊髓束变化的意义。方法回顾性分析50例脑白质疏松患者的DTI影像,测量不同Mantyla分级脑白质疏松症患者的FA值、ADC值、CSF纤维数量及纤维长度。结果不同分级患者的FA值、ADC值、CSF纤维数量及左CSF纤维长度差别均有统计学意义(P<0.05或<0.01)。结论磁共振DTI技术对观察不同Mantyla分级脑白质疏松症患者皮质脊髓束变化具有重要意义,其可以定量分析皮质脊髓束在脑白质疏松症不同分级间的变化。

Objective To explore the DTI technology to observe the significance of change of corticospinal tract of patients with different Mantyla grading of brain white matter. Methods DTI images of 50 cases of patients with white matter of the brain were retrospectively analyzed.The FA value, ADC value,CSF fiber number and fiber length of patients with different Mantyla grading of brain white matter were measured. Results The differences of FA value,ADC value,CSF fiber number and fiber length of patients with different Mantyla grading of brain white matter were all statistically significant （P 〈 0.05 or 0.01）. Conclusion Magnetic resonance DTI technology has great significance on observing the significance of change of corticospinal tract of patients with different Mantyla grading of brain white matter.h can quantitatively analyze the change of corticospinal tracts in corticospinal tract in different leukoaraiosis grading.