大连地区中老年人群中颈围与高血压的相关性研究

Correlation of neck circumference with hypertension in middle-aged and elderly people in Dalian

目的 ：探讨辽宁大连地区中老年人群中颈围与高血压间的相关性。方法 ：对参加＂2型糖尿病肿瘤发病风险流行病学研究＂基线调查的辽宁省大连市社区居民进行随访,共纳入符合标准的研究对象2 623名,对其进行问卷信息收集,并进行体格检查及生化检测。根据颈围四分位数水平,将其分为Q1、Q2、Q3及Q4组,比较各组间的收缩压、舒张压和高血压患病率及其他临床指标。结果：颈围四分位Q1、Q2、Q3及Q4组间的收缩压、舒张压差异均有统计学意义,收缩压分别为（121.4±16.9）、（122.6±16.7）、（128.5±18.6）、（132.0±18.2）mm Hg,舒张压分别为（70.8±9.7）、（73.1±9.4）、（75.7±10.5）及（77.4±10.0）mm Hg（P均〈0.001）,且随着颈围的增加,收缩压及舒张压逐渐升高。4组的高血压患病率分别为16.8%、17.7%、29.3%及38.5%,差异有统计学意义（χ2=104.955,P〈0.001）。颈围与收缩压及舒张压均呈正相关（r为0.273、0.324,P〈0.05）。多元线性逐步回归分析显示,颈围水平增加与收缩压、舒张压水平增加间显著相关。Logistic回归分析结果显示,颈围每增加一个标准差,高血压患病风险增加41.2%（OR=1.412,95%CI为1.216~1.639,P〈0.001）。结论 ：大连地区中老年人群中,随着颈围增加,收缩压及舒张压水平逐渐增加,高血压患病率亦有逐渐增加趋势,研究结果提示颈围是大连地区中老年人高血压患病的独立危险因素。

Objective： To investigate the correlation between neck circumference and hypertension in middle-aged and el- derly people in Dalian. Methods： Residents who participate the Epidemiological Study on Cancer Risk in Type 2 Diabetes Mel- litus Patients were recruited in this study. Ahogether 2 623 residents aged 45-year-old or older were recruited. Participant＇s histo- ry, results of physical examination and blood test were recorded. According to the neck circumference quantile, the participants were divided into group Q1, group Q2, group Q3 and group Q4. The prevalence of hypertension and other clinical parameters were compared between the four groups. Results： Levels of systolic blood pressure （SBP） and diastolic blood pressure （DBP） were significantly different between the four groups （P〈0.001）. The prevalences of hypertension in the four groups were statistically dif- ferent （X2=-104.955, P〈0.001）. Pearson correlation coefficient analysis showed that neck circumference was positively correlated with SBP and DBP （r=0.273,r=0.324, P〈0.05）. Neck circumference was correlated with SBP or DBP in multivariate linear regres- sion analysis. The binary logistic regression analysis showed that the prevalence of hypertension increased by 1.412 fold per SD increase in neck circumference （OR=1.412, 95%CI： 1.216-1.639, P〈0.001）. Conclusions： SBP and DBP increase with increase in neck circumference in residents of Dalian. With an increase in neck circumference, the prevalence of hypertension increases accordingly. Neck circumference is an independent risk factor for hypertension in middle-aged and elderly people in Dalian.