人参养营汤治疗支气管哮喘慢性持续期60例

Sixty Cases of Bronchial Asthma During Chronic Duration Treated with Ginseng Supporting and Nourishing Decoction

目的:观察人参养营汤治疗肺肾气虚型支气管哮喘慢性持续期的临床疗效。方法:选取120例肺肾气虚型支气管哮喘慢性持续期患者为研究对象,随机分为对照组和研究组,每组各60例。对照组给予西医对症治疗,研究组在对照组的基础上加用人参养营汤治疗,观察两组患者治疗前后免疫功能(Ig A、Ig G、Ig M、Ig E),肺功能[第1秒用力呼气量(Forced expiratory volume in the first second,FEV1)、最大呼气流速(peak expiratory flow,PEF)及用力肺活量(Forced vital capacity,FVC)],哮喘控制测试(Asthma control test,ACT)及中医症状体征积分的变化情况。结果:治疗后对照组患者Ig A、Ig G、Ig M、Ig E水平与治疗前比较,差异无统计学意义(P>0.05);治疗后研究组患者Ig A、Ig E水平均优于治疗前,且研究组优于对照组,差异均有统计学意义(P<0.05)。治疗后两组患者FEV1、PEF、FVC水平均高于同组治疗前,且研究组优于对照组,差异均有统计学意义(P<0.05)。治疗后两组患者ACT总积分高于治疗前,且研究组高于对照组,差异均有统计学意义(P<0.05),治疗后两组患者中医症状体征总积分低于治疗前,且研究组低于对照组,差异均有统计学意义(P<0.05)。对照组显效率为68.3%,研究组显效率为90.0%,两组患者显效率比较,差异具有统计学意义(P<0.05)。结论:人参养营汤治疗肺肾气虚证支气管哮喘慢性持续期患者,安全有效,可能与提高患者免疫水平相关。

Objective ：To observe the clinical curative effect of Ginseng Supporting and Nourishing Decoction on bronchial asthma during chronic duration of lung-kidney qi deficiency syndrome. Methods ： One hundred and twenty patients with bronchial asthma during chronic duration of lung-kidney qi deficiency syndrome were chosen as the research objects, and were randomly divided in- to the control group and the research group ,with 60 cases in each group. The ones in the control group were given routine Western medicine symptomatic treatment, while the ones in the research group were added Ginseng Supporting and Nourishing Decoction based on the treatment of the control group. Then the two groups＇ immune function （including IgA, IgG, IgM and IgE） before and after the treatment, forced expiratory volume in the first second （FEV1）,peak expiratory flow （PEF）, forced vital capacity （FVC）, asthma control test （ACT） and TCM symptom sign scores change were observed. Results：After the treatment, the differences in IgA, IgG, IgM and IgE of the control group had no statistical significance （ P 〉0. 05）.After the treatment, IgA and IgE levels of the research group were all better than those of the control group;The research group was better than the control group, and all the differences between them had significance （ P 〈 0.05 ）. After the treatment. FEV1, PEF and FVC levels of the two groups were all higher than those of the same group before the treatment;The research group was better than the control group, and all the differences between them had significance （ P 〈 0.05 ）. After the treatment, the two groups＇ total scores of ACT were higher than those before the treatment ,the research group was better than the control group ,and the difference between them had significance （ P 〈 0. 05 ）. After the treatment, the two groups＇ total scores of TCM symptoms and signs were lower than those before treat- ment, the research group was lower than the control group, and all the differences between them had significance （ P 〈 0. 05 ）. The significant efficiency of the control group was 68.3% ,while that of the research group was 90% ;the difference between them was statistically significant （ P 〈 0.05 ）. Conclusion： Ginseng Supporting and Nourishing Decoction has a safe curative effect on bronehial asthma during chronic duration of lung-kidney qi deficiency syndrome, and may be related to improving the immune status of the patients.