血液净化在儿童横纹肌溶解症治疗中的应用价值研究

Study on application value of blood purification in treating child rhabdomyolysis

目的探讨血液净化在儿童横纹肌溶解症治疗中的应用价值。方法 13例横纹肌溶解症患儿入院后立即予以血液净化治疗。检测患儿血液净化治疗前后血肌红蛋白(Mb)、肌酸磷酸激酶(CPK)、肌酸磷酸激酶同工酶(CPK-MB)、乳酸脱氢酶(LDH)、丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)、血尿素氮(BUN)、血肌酐(Cr)的变化情况,并观察临床改善情况。结果经过血液净化治疗后患儿Mb、CPK、CPK-MB、LDH、ALT、AST、BUN、Cr均有明显好转,临床表现明显改善。结论血液净化对治疗儿童横纹肌溶解症有着良好的效果。

Objective To investigate the application value of blood purification in child rhabdomyolysis. Methods Thirteen children patients with rhabdomyolysis were given the blood purification therapy instantly after admission. Serum levels of myohemoglobin （Mb）, creatine phosphokinase （CPK）, creatine phosphokinase isoenzyme （CPK-MB）, lactate dehydrogenase （LDH）, alanine aminotransferase （AL.T）,aspartate aminotransferase （AST）,urea nitrogen （BUN） and creatinine （Cr） were measured before and after blood purification. The clinical improvement situation was observed. Results After blood purification therapy, the average serum levels of Mb, CPK, CPK-MB, LDH, ALT, AST, BUN and Cr were significantly improved, moreover the clinical manifestations were obviously improved. Conclusion Blood purification has better effect in treating child rhabdomyolysis.