2Prass K,Meisel C, H6flich C, et al. Stroke-induced immunode- ficiency promotes spontaneous bacterial infections and is medi- ated by sympathetic activation reversal by poststroke T helper cell type l-like immunostimulation [J]. J Exp Med, 2003, 198 (5) : 725-736.
3Famakin BM. The immune response to acute focal cerebral is- chernia and associated post-stroke irnmunodepression., a fo- cused review[J]. Aging Dis, 2014,5 ( 5 ) : 307-326.
4Chang LL, Chen YT, Li J, et al. Cocaine-and amphetamine-reg- ulated transcript modulates peripheral immunity and protects against brain injury in experimental stroke[J]. Brain Behav Im- mun, 2011,25 (2) : 260-269.
5Nakajima K,Kohsaka S. Microglia: activation and their signifi- cance in the central nervous system[J]. J Biochem, 2001,130 (2) : 169-175.
6Pun PB, Lu J, Moochhala S. Involvement of ROS in BBB dys- function[J]. Free Radic Res, 2009,43 (4) : 348-364.
7Cuenca-Lopez MD, Brea D, Galindo MF, et al. Inflammatory re-sponse during ischaemic processes: adhesion molecules and im- munomodulation[J]. Rev Neurol, 2010,51 (1) : 30-40.
8Seifert HA, Pennypaeker KR. Molecular and cellular immune responses to ischernic brain injury[J]. Transl Stroke Res, 2014,5(5) :543-553.
9Konoeda F, Shichita T, Yoshida H, et al. Therapeutic effect of IL-12/23 and their signaling pathway blockade on brain ische- mia model[J]. Biochem Biophys Res Commun, 2010,402(3): 500-506.
10Brait VH, Arumugam TV, Drummond GR. Importance of T lymphocytes in brain injury, immunodeficiency, and recovery after cerebral ischemia[J]. Journal of Cerebral Blood Flow and Metabolism, 2012,32 (4) : 598-611.
二级参考文献21
1Jickling GC,Xu H,Stamova B,et al. Signatures of cardioem bolic and large vessel ischemic stroke. Ann Neurol,2010,68: 681-692.
2l.indsberg PJ, Strbian D, Karjalainen Lindsberg ML: Mast cells as early responders in the regulation of acute hlood brain barrier changes after cerebral ischemia and hemorrhage. J Cereb Blood Flow Metab,2010,30:689-702.
3Swirski FK, Nahrendorf M. Leukocyte behavior in atheroscle rosis, myocardial infarction, and heart failure. Science, 2013, 339:161-166.
4Mao SS, Hun R, Zhao XP, et al. Exogenoas administration of PACAP alleviates traumatic brain injury in rats through a mechanism involving the TLR4/MyD88 /NF-κB; pathway. J Neurotrauma,2012,29: 1941-1959.
5Zeng KW, Zhang T, Fu H, et al. Schisaldrin β exerts ami ne,aroinflammatory activity by inhibiting the Toll-like recep tor 4 dependent MyD88/IKK/NF-κB signaling pathway in li- popolysaccharide induced microglia. Eur J Pharmacol, 2012, 692:29-37.
6Zhang P,Liu X,Zhu Y,et al. Honokiol inhibits the inflamma- tory reaction during cerebral ischemia reperfusion by sup pressing NE-κB activation and cytokine production of glial cells. Neurosci Lett,2013,534 : 123-127.
7Wang Z, Wu L, You W, et al. Melatonin alleviates secondary brain damage and neurobehavioral dysfunction after experi mental subarachnoid hemorrhage: possible involvement of TLR4 mediated inflammatory pathway. J Pineal Res, 2013, 55:399-408.
8Zhang H, Li X. Correlation between inflammatory factors and post stroke pneumonia in diabetic patients. Exp Ther Med, 2013,6:105-108.
9Emsley HC, Hopkins SJ. Post stroke inmmnodepression and infection:an emerging concept. Infect Disord Drug Targets, 2010,10:91-97.
10Offner H, Vandenbark AA, Hurn PD. Effect of experimental stroke on peripheral immunity: CNS ischemia induces profo und immunosuppression. Neuroscience, 2009,158 : 1098-1111.
