联用自体骨粉乳突腔填塞、外耳道重建及开放式鼓室成形术对胆脂瘤型中耳炎的疗效观察

Combined application of mastoid obliteration with autologous bone powder, canal wall reconstruction and open tympanoplasty in cholesteatomatous tympanitis

目的观察联用自体骨粉乳突腔填塞、外耳道重建及开放式鼓室成形术治疗胆脂瘤型中耳炎效果。方法84例胆脂瘤型中耳炎患者随机分成对照组和治疗组,分别采用常规开放式鼓室成形术治疗和自体骨粉乳突腔填塞+外耳道重建术+开放式鼓室成形术,观察两组疗效、干耳率及干耳时间。结果两组疗效差异无统计学意义(P>0.05)。治疗组干耳率明显高于对照组(92.9%vs 59.5%),而干耳时间短于对照组[(29.6±8.4)d vs(38.1±10.7)d],差异均有统计学意义(P<0.01)。结论联用自体骨粉乳突腔填塞、外耳道重建及开放式鼓室成形术对胆脂瘤型中耳炎具有较好疗效,可提高干耳率和缩短干耳时间。

Objective To observe the combined use of mastoid obliteration with autologous bone powder （MOABP）, canal wall reconstruction （CWR） and open tympanoplasty （OTP） in cholesteatomatous tympanitis. Methods Eighty-four patients with cholesteatomatous tympanitis were randomly divided into control and treatment groups, and then treated with conventional OTP and combined use of MOABP, CWR and OTP. Clinical efficacy and dry ear rate and time were compared between both groups. Results Clinical efficacy showed no significant difference between both groups （P〉0.05）. Compared with control group, dry ear rate was increased but dry ear time decreased （P〈0.05） in treatment group. Conclusion Combined usage of MOABP, CWR and OTP is effective for cholesteatomatous tympanitis, which can improve dry ear rate and shorten dry ear time.