严重高钙血症发生机制及救治

Pathogenesis and therapeutic strategy of severe hypercalcemia

钙是人体中必不可少的元素，在骨形成、激素释放和肌肉收缩神经传导方面具有重要作用。高钙危象属于内分泌急症，需要进行紧急救治，以免产生严重后果。儿童高钙危象发生虽然远远低于成人，但由于其临床症状重，更应引起临床医生警惕。本文对严重高钙血症的诊断、鉴别诊断及治疗原则等方面进行归纳总结。

Calcium is an essential element for the formation of bone,hormone release,muscle con-traction and nerve conduction. Hypercalcemia is rare in pediatrics. However, hypercalcemia crisis must be treated urgently because it often can lead to cardiac arrhythmia, cardiac arrest, circulatory failure and death consequently. It also causes severe neurological symptoms or progressive renal failure. Clinically,it should be worked out the causes of hypercalcemic crisis as soon as possible so as to treat relevantly. This article de-scribed the tests,etiologies,combined with drugs and surgical treatment to achieve the best therapeutic effect.