颈动脉粥样硬化对冠心病预测意义的研究进展

Research progress of significance of carotid artery atherosclerosis in prediction of coronary heart disease

冠心病是严重威胁人类健康、引起死亡的主要心血管疾病。近年来,随着生活水平的不断提高以及生活方式的转变,冠心病的发病率逐年增高,并有进一步向年轻化发展的趋势,因此,如何早期、准确诊断冠心病显得尤为重要。大量研究表明,颈动脉粥样硬化与冠心病的发病及严重程度相关。彩色多普勒超声以其经济、简便、无创等优点已成为临床检测动脉粥样硬化的主要方法,超声检测粥样硬化的严重性可以有效判断冠心病的病情发展,因此,通过颈动脉超声检测动脉内中膜厚度及斑块情况间接反映冠状动脉粥样硬化程度成为国内外研究的热点。本文通过阅读大量文献,对近年来超声下颈动脉粥样硬化对冠心病预测意义的研究进展做如下综述。

Coronary heart disease is a serious threat to human health which is also a primary cardiovascular disease that causes death.With rising living standards,lifestyle changes in recent years,the incidence rate increased year by year,there is a trend towards younger development,how early and accurate diagnosis of coronary heart disease is particu- larly important.A large number of studies shows that carotid artery atherosclerosis is relevant to the morbidity and severity of coronary atherosclerotic heart disease.Color Doppler ultrasound has become the main checking method of clinical detection of peripheral atherosclerosis on account to its merits of economy,simplification and noninvasiveness. The severity of atheroselerosis by ultrasonic inspection and measurement can effectively judge the development of coro- nary heart disease.Therefore,indirect reflected by peripheral artery ultrasound detection of arterial intima-media thick- ness and plaque of coronary atherosclerosis has become a hot research at home and abroad.Through reading a lot of lit- eratures,this paper reviews the research progress of the predictive value of carotid atheroselerosis in patients with coro- nary heart disease in recent years.