胸腔内灌注药物治疗肺术后持续性漏气的临床比较分析

The clinical comparative analysis about the treatment of the pouring drug into thoracic cavity for the postoperative sustained pulmonary air leakage

目的探讨不同药物胸腔内灌注治疗肺术后持续性漏气患者的疗效,并对灌药后相关指标进行对比分析。方法收集自2009年10月至2015年1月行肺手术后出现肺持续性漏气的患者60例,行胸腔灌注治疗:50%葡萄糖20例(A组)、红霉素20例(B组)、自体血治疗剂组20例(C组),观察胸痛、胸闷、心率、体温、住院时间、住院费用及疗效等指标,并对其进行对比分析。结果疗效观察:A组治愈率90%,显效率10%;B组治愈率85%,显效率15%;C组治愈率95%,显效率5%。用药后出现胸闷表现:A组4例,B组8例,C组5例。胸腔灌药后出现胸痛表现:B组7例。A组分别与B组和C组比较,胸腔灌药后心率变化及体温变化有差别(P<0.05);3组住院时间、住院费比较无差别(P>0.05)。结论 3种治疗方法均能有效地治疗肺术后持续性漏气,并且达到较满意的疗效。

Objective To probe the effect of pouring different drug into thoracic cavity for treating the postoperative sustained pulmonary air leakage. Methods From October 2009 to January 2015,60 cases were collected, the groupof 50% glucose （ group A） consists of 20 cases ; the group of erythromycin （ group B） consists of 20 cases; the group of autologous blood treatment consists of 20 cases （group C ）, then we observed thoracalgia, oppression in the chest, heart rate, body temperature,length of hospital stay, hospital expenses and analysed the data. Results Group A cure rate ：90%, significant efficiency ： 10%, group B cure rate ： 85 %, significant efficiency ： 15 %, group C cure rate ：95 %, significant efficiency ：5%. Oppression in the chest after the drug perfused ： group A 4 cases, group B 8 cases, group C 5 cases. Chest pain after infusion of medicine：group B 7 cases. There were significant difference in the heart rate and temperature among the three groups （P 〈 0.05）. There were no difference in the length of hospital stay and hospital expenses among the three groups （P 〉 0.05）. Conclusion Three treatment methods can effectively treat pulmonary postoperative continuous air leakage in thoracic surgery, and achieve satisfactory curative effect.