抗生素联合激素治疗夜间急诊牙痛的临床研究

Clinical study of antibiotics combined with hormone in the treatment of emergency toothache at night

目的:研究抗生素联合激素在夜间急诊牙痛患者中的临床治疗效果,为临床治疗提供依据。方法:选取2014年3月-2016年3月医院诊治的夜间急诊牙痛患者60例,依据治疗措施分为对照组30例和观察组30例。对照组采用常规口服布洛芬控制疼痛,观察组采用抗生素联合激素控制急性疼痛。比较两组的临床疗效、药物起效时间、止痛持续时间,以及药物不良反应等相关指标。结果:两组均能有效控制急诊牙痛,而抗生素联合激素组治疗有效率显著高于布洛芬组(93.3%vs 80.0%,P<0.05);抗生素联合激素组患者药物治疗后疼痛起效时间、止痛持续时间等有效性指标显著优于布洛芬组(P<0.05);同时不良反应发生率显著低于布洛芬组(P<0.05)。结论:与常规口服布洛芬止痛治疗相比,采用抗生素联合激素治疗夜间急诊牙痛患者能更有效缓解患者疼痛,为患者后续治疗做好准备,值得临床推广应用。

AIM： To investigate the therapeutic effect of antibiotics combined with hormone in emergency toothache patients so as to provide the reference for clinical treatment. METHODS： 60 cases with emergency toothache at night from March 2014 to March 2016 in our hospital were enrolled,and were divided into control group and observation group（ 30 cases in each） based on treatment measures. The control group was treated with conventional oral Fenbid,while the observation group was received with antibiotics combined with hormone therapy. The clinical efficacy,the analgesic onset time,and the duration of the analgesia in two groups were compared. RESULTS： The curative effect rate（ 93. 3%） in the observation group was significantly higher than that in the control group（ 80. 0%）（ P〈 0. 05）. The analgesic onset time in observation group was significantly shorter than that of the control group（ P 〈 0. 05）. The duration time of pain relief in the observation group was longer than that in the control group（ P 〈 0. 05）. The incidence of adverse reactions in the observation group was 13. 4%,which was significantly lower than that of 40. 0% in control group（ P 〈 0. 05）. CONCLUSION： Compared with conventional oral analgesic therapy,combination of antibiotics with hormone in the treatment of emergency toothache patients at night manifests an ideal effect,and can alleviate the pain of patients,which is worth of clinical application.