期刊文献+

外周T细胞淋巴瘤的靶向治疗进展 被引量:1

原文传递
导出
摘要 外周T细胞淋巴瘤(PTCL)是一组起源于胸腺的成熟T细胞的淋巴增殖性疾病。与B细胞淋巴瘤相比,PTCL侵袭性更强、预后更差,治疗上缺乏统一的标准治疗方案。传统化学治疗方案CHOP(环磷酰胺+长春新碱+多柔比星+泼尼松)及CHOP类似方案对PTCL疗效欠佳。造血干细胞移植在PTCL中的应用有限。因此PTCL的治疗正成为淋巴瘤治疗中最具前沿性和挑战性的研究领域。随着临床研究的不断进展,靶向药物在PTCL的治疗上显示出一定的前景。该文就其靶向治疗进行了综述。
作者 李娜 邹立群
出处 《华西医学》 CAS 2016年第11期1943-1948,共6页 West China Medical Journal
  • 相关文献

参考文献1

二级参考文献24

  • 1Asano N, Suzuki R, Kagami Y, et al. Clinicopathologic and prognostic significance of cytotoxic molecule expression in nodal peripheral T-cell lymphoma, unspecified. Am J Surg Pathol, 2005, 29 : 1284-1293.
  • 2Pescarmona E, Pignoloni P, Puopolo P, et al. p53 overexpression identifies a subset of nodal peripheral T-cell lymphomas with a distinctive biological profile and poor clinical outcome. J Pathol, 2001,195:361 -366.
  • 3Rodriguez J, Caballero MD, Gutierrez A, et al. High-dose chemotherapy and autologous stem cell transplantation in peripheral T- cell lymphoma: the GEL-TAMO experience. Ann Oncol, 2003, 14 : 1768-1775.
  • 4Song KW, Mollee P, Keating A, et al. Autologous stem cell transplant for relapsed amt refractory peripheral T-cell lymphoma: variable outcome according to pathological subtype. Br J Haematol, 2005, 120:978-985.
  • 5Rodriguez J, Conde E, Gutierrez A,et al. The adjusted International Prognostic Index and beta-2-microglobulin predict the outcome after autologous stem cell transplantation in relapsing/refractroy peripheral T-cell lymphoma. Haematologica, 2007, 92: 1067-1074.
  • 6Corradini P, Tarella C, Zallio F, et al Long-term follow-up of patients with peripheral T-cell lymphomas treated up-front with highdose chemotherapy followed by autologous stem cell transplantation. Leukemia, 2006, 20:1533-1538.
  • 7Rodriguez J, Conde E, Gutierrez A, et al. Frontline autologous stern cell transplantation in high-risk peripheral T-cell lymphoma: a prospective study from The Gel-Tamo Study Group. Eur J Haematol, 2007, 79:32-38.
  • 8Reimer P, Ruediger T, Schertlin T, et al. Autologous stem cell transplantation as first-line therapy in peripheral T-cell lymphomas. A prospective multicenter study. Blood, 2005,106: 2074.
  • 9Corradini P, Dodero A, Zallio F, et al. Graft-versus-lymphoma effect in relapsed peripheral T-cell non-Hodgkin's lymphomas after reduced-intensity conditioning followed by allogeneic transplantation of hematopoietic cells. J Clin Oncol, 2004, 22:2172-2176.
  • 10Majhail NS, Burns LJ. Hematopoietic stem cell transplantation in the treatment of peripheral T-cell lymphomas. Curr Hematol Rep, 2005, 4:252-259.

共引文献3

同被引文献4

引证文献1

二级引证文献9

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部