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足细胞相关分子在临床诊治实践中的意义与思考 被引量:3

Significance of podocyte-related molecules in clinical practice of diagnosis and treatment and some thoughts about it
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摘要 蛋白尿是儿童肾脏疾病最为常见的临床症状,在其发生和进展的分子机制中,足细胞起到非常重要的作用,越来越多的足细胞相关分子已经被证实与蛋白尿发生的分子机制相关,但是在蛋白尿的诊疗中,这些分子还没有被真正地转化为临床所用。该文以足细胞致蛋白尿发生的分子机制为切入点,探讨其在蛋白尿的监测和治疗两个方面的进展及思考。 Proteinuria is the most common manifestations of pediatric renal diseases. During the development and process of proteinuria,podocytes have played a very important role. A growing number of podocyte-related molecules have been confirmed to be associated with the molecular mechanisms of proteinuria. However,there are few studies focusing on the role of podocyte-related molecules in the diagnosis and treatment of proteinuria. Due to the lack of real transformation from bench to bed situation,the present paper will discuss the role of podocyte in the monitoring and treatment of proteinuria based on the podocytes’ role in mechanisms of proteinuria.
作者 丁洁 丁方睿
出处 《中国实用儿科杂志》 CSCD 北大核心 2016年第11期801-805,共5页 Chinese Journal of Practical Pediatrics
关键词 蛋白尿 足细胞 肾小球 proteinuria podocyte glomeruli
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  • 1Luo Y, Wang C, Chen X, et al.lncreased serum and urinary mi- croRNAs in children with idiopathic nephrotic syndrome [J]. Clin Chem, 2013,23. [ Epub ahead of print ].
  • 2Zhang G, Li Q, Wang L, et al.The effects of imflammation on lip- id accumulation in the kidneys of children with primary nephrit- ic syndrome [ J .Inflammation, 2011,34 (6) : 645-652.
  • 3Niu XL, Kuang XY, Zhang ZG, et al.Expression of response gene to complement-32 in renal tissue of children with immunoglobu- lin A nephropathy [J].Scanc[ J Urol Nephrol, 2011,45 (5) : 371-376.
  • 4Zhou TB, Yin SS.Association of matrix metalloproteinase-9 lev- el with the risk of renal involvement for Henneh-Schnlein Pur- pura in children [ J ].Ren Fail, 2013,29.[ Epub ahead of print.
  • 5Wu FQ, Zhao Q, Cui XD.C 1 q and anti-C l q antibody levels are correlated with disease severity in Chinese pediatric: systemic: lupus erythematosus [ J ].Rheumatol Int, 2011,31 (4) : 501-505.
  • 6Tang JH, Wen Y, Wu F, et al.Increased plasma acy|ation-stim- ulating protein in pediatric proteinuric renal disease [J].Pedi- atr Nephrol, 2008,23 ( 6 ) : 959-964.
  • 7Lu H, Zhu H, Zhou J.S gene mutations of HBV in children with HBV-associated glomerulonephritis [J .Virol J, 2012, 59 (9) :2-6.
  • 8Li X, Huang A, Zhou P, et al.Differences in tissue expression of HBV markers in children with HBV-associated glomerulo- nephritis[J].Ren Fail,2011, 33(9) :885-891.
  • 9Zhang Y, Wang F, Ding J, et al.Genotype-phenotype correla- tions in 17 Chinese patients with autosomal recessive Alport syndrome[J].Am J Med Genet A,2012,158A(9) :2188-2193.
  • 10Yang ZH, Zhang CM, Liu T, et al.Continuous renal replacement therapy for patients with acute kidney injury caused by melamine-related urolithiasis[J].World J Pediatr,2010,6(2) :158-62.

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