腰椎间盘突出症臭氧消融术后短期内复发的危险因素

Risk factors for the short- term recurrence of protrusion of lumbar intervertebral disc after ozone ablation

目的 探讨腰椎间盘突出症臭氧消融术后短期内复发的相关危险因素。方法 将2011年1月至2015年6月臭氧消融术治疗腰椎间盘突出症6个月内复发的40例患者作为观察组，并随机选取同期术后无复发40例患者作为对照组，对可能影响复发的11项因素采用t/χ^2检验进行单因素分析，对有统计学意义的单因素进行多因素非条件Logistic回归分析。结果 单因素分析显示病程、腰椎间盘退变、臭氧在盘内分布、术后过早负重等因素与腰椎间盘突出症臭氧消融术后短期内复发有关，差异有统计学意义（P〈0.05）。多因素非条件Logistic回归分析显示腰椎间盘突症臭氧消融术后复发与病程、腰椎间盘退变、术后过早负重有关，差异有统计学意义（P〈0.05）。结论 患者病程大于3年、腰椎间盘退变、术后过早负重是腰椎间盘突出症臭氧消融术后短期内复发的独立危险因素。

Objective To investigate the risk factors for the short-term recurrence of protrusion of lumbar intervertebral disc after ozone ablation. Methods A total of 40 patients with protrusion of lumbar intervertebral disc, who had a relapse within six months after ozone ablation treatment that was performed during the period from January 2011 to June 2015, were collected and used as the observation group; and other 40 patients with protrusion of lumbar intervertebral disc, who had no relapse after ozone ablation treatment during the same period, were randomly selected and used as the control group. By using t/χ^2 test, single factor analysis of 11 factors that might affect the recurrence was conducted, and Logistic regression analysis was adopted to evaluate these single factors that had statistical significance. Results Univariate analysis showed that the course of disease, lumbar disc degeneration, the distribution of ozone in the lumbar disc and postoperative early weight-bearing, etc. were related to the short-term recurrence of protrusion of lumbar intervertebral disc after ozone ablation, the differences were statistically significant （P〈0.05）. Multiple factor non-conditional Logistic regression analysis indicated that the short-term recurrence of protrusion of lumbar intervertebral disc after ozone ablation was linked to the course of disease, lumbar disc degeneration and postoperative early weight-bearing, the differences were statistically significant （P〈0.05）. Conclusion The results of this study indicate that the course of disease 〉3 years, lumbar disc degeneration and postoperative early weight-bearing are the independent risk factors responsible for the short-term recurrence of protrusion of lumbar intervertebral disc after ozone ablation.