24例孤立性左主干狭窄病变患者临床特点及预后分析

Analysis of the Characteristics and Prognosis of Adult Patients With Isolated Left Main Coronary Artery Stenosis

目的总结孤立性左主干狭窄病变患者的临床特点及预后。方法回顾性分析2010年1月-2016年6月于我院心内科住院行冠脉造影术并诊断为孤立性左主干狭窄的患者,比较开口病变组和非开口病变组的临床特点及预后。结果 13 618例行冠脉造影患者中共24例（0.18%）诊断孤立性左主干狭窄,其中开口病变组13例（54.2%）、非开口病变组11例（45.8%）,两组分别有12例和8例接受了支架植入术,平均近2年的随访期内无死亡病例。相比非开口病变组,开口病变组女性比例高、高密度脂蛋白更低,而在其他临床特征、血运重建方式、短期及远期预后上差异无统计学意义。结论孤立性左主干狭窄病变患者在接受支架植入术后短期及远期预后较好。

Objective To summarize the clinical features and prognosis of patients with isolated left main stenosis. Methods Patients hospitalized for coronary angiography and diagnosed with isolated LMCA stenosis in the cardiology department from January 2010 to June 2016 were reviewed retrospectively. Comparisons between patients with ostial and nonostial stenosis in clinical features and prognosis were conducted. Results Among 13 618 patients who underwent coronary angiography, 24 patients（0.18%） were diagnosed with isolated LMCA stenosis 13 ostial stenosis（54.2%） and 11 nonostial stenosis（45.8%）. 12 cases in ostial stenosis group and 8 cases in nonostial stenosis group received stent implantation, and no one died in almost two-years follow-up. Compared with nonostial stenosis, patients with ostial lesions had more females and low HDL-C level. Other clinical characteristics, short and long-time outcomes were similar between two groups. Conclusion Patients with isolated left main stenosis underwent short and long-term prognosis after stent implantation.