中药塌渍联合肿瘤坏死因子拮抗剂治疗活动性强直性脊柱炎的临床观察

Clinical Observation of Patients With Active Ankylosing Spondylitis Treated by Combination of Chinese Medicine Collapse Stains and Tumor Necrosis Factor

目的探讨中药塌渍联合肿瘤坏死因子拮抗剂治疗活动性强直性脊柱炎的临床效果。方法将活动性强直性脊柱炎患者74随机分两组,对照组37例采用肿瘤坏死因子拮抗剂治疗,观察组37例采用中药塌渍联合肿瘤坏死因子拮抗剂治疗。结果观察组晨僵时间、红细胞沉降率、C反应蛋白、VAS评分、BASDAI评分、BASFI评分低于对照组,而治疗优良率高于对照组(P<0.05)。结论中药塌渍联合肿瘤坏死因子拮抗剂是治疗活动性强直性脊柱炎的有效方法,临床疗效显著。

Objective To investigate the clinical effect of treating ankylosing spondylitis with the combination of Chinese medicine collapse stains and tumor necrosis factor antagonist. Methods 74 patients with active ankylosing spondylitis were randomly divided into two groups, 37 cases in control group treated TNF antagonist. 37 cases in observation group treated collapse stains combined with tumor necrosis factor antagonist treatment. Results The observation group of morning stiffness time, erythrocyte sedimentation rate, C reactive protein, VAS score, BASDAI score, BASFI score lower than the control group, and the treatment was higher than that of control group（P0.05）. Conclusion The combination of Chinese medicine and tumor necrosis factor antagonist is an effective method to treat active ankylosing spondylitis, and it is helpful to improve clinical effect.