英国兽药理事会批准的可用于马匹的兽药产品分析

Analysis of Equine Medicine Products Authorized by Veterinary Medicines Directorate United Kingdom

为了探究英国兽药理事会(VMD)批准上市的马匹兽药产品情况,从VMD 2016年3月提供的产品信息数据库统计分析。结果显示,上市的可用于马匹的兽药产品占兽药总数的12%,而马匹专属产品占6%;1990年-2015年年均批准马匹用兽药产品约12个;持有上市总兽药以及马匹兽药数量最多的前3个企业依次为Norbrook laboratories Ltd,Zoetis UK Ltd和Intervet UK Ltd;批准产品中抗炎药、中枢神经系统药和抗寄生虫药比例最高;优势兽药活性成分中非甾体抗炎药美洛昔康、抗寄生虫药伊维菌素及其同吡喹酮复方和镇静剂甲苯噻嗪获批产品数名列前3位;从给药途径来看,注射给药产品占62%,而口服产品占27%,外用和吸入给药产品比例较低。以上统计结果说明国际兽药企业注重马匹用药在英国的审批和上市,从马匹用兽药优势品种和主要活性成分可以提示马匹用药热点,该统计结果为管理和制定同国际接轨的我国马匹用药标准提供参考。

To understand the condition of equine medicine products authorized by Veterinary Medicines Directorate（VMD）,United Kingdom,the present study statistically analyzed the Product Information Database provided by VMD in March,2016.The results showed that 12% of veterinary medicine products could be used for horses,and6% of them were only used for horses.From 1990 to 2015,the authorized equine medicine products were 12 annually.The most amounts of product pharmaceutical holders were Norbrook Laboratories Ltd,Zoetis UK Ltd and Intervet UK Ltd.The three highest proportion of equine products were anti-inflammatory,central nervous system and anti-parasitic medicines.The top three main active substances used for horses were meloxicam,ivermectin and its compound with praziquantel,and xylazine.Sixty two percentage of equine medicine products were injection form,and 27% of them were orally administrated,while the proportion of topical and inhalation products was low.Those statistical results indicate that the famous international veterinary pharmaceutical companies are interested in applying equine medicines in UK,and the popular equine medicine products and the active substances showed the most requirement medicines for horses in UK.Meanwhile,the statistical results can be refereed to establish Chinese equine medicines guidance which is related to the international guidance.