复方樟柳碱对于玻璃体切割术后面向下体位患者眼底血液循环的作用

The Function of Compound Anisodine for Vitrectomy Down Behind the Position of the Patient's Fundus Blood Circulation

目的:观察复方樟柳碱对于玻璃体切割术后面向下体位患者的眼底血液循环的作用。方法:将80例拟行玻璃体切割联合硅油填充手术的孔源性视网膜脱离患者随机分为两组,观察组(n=40)于术后第1天注射复方樟柳碱,连续注射2周,并测量术后1d、14d的视网膜微循环血流参数[包括血容量(Volume)、血流量(Flow)、红细胞移动速率(Velocity)],对照组(n=40)不给予额外的扩血管药物,测量时间、内容和方法与观察组同。结果:对照组术后14d的Vol、Flw、Vel均较治疗后1d减少,差异具有统计学意义(P均<0.05),观察组术后14d的Vol、Flw、Vel均较治疗后1d增加,差异具有统计学意义(P均<0.05),两组患者术后14d的Vol、Flw、Vel比较差异具有统计学意义(P均<0.05)。结论:复方樟柳碱对于玻璃体切割术后面向下体位患者的眼底血液循环有着改善作用,能够减少继发性眼底缺血,改善患者的视觉质量,具有较高的临床应用价值。

Objective：Objective：To observed the function of compound anisodine for vit-rectomy down behind the position of the patient＆#39;s fundus blood circulation. Methods： 80 cases of the use of vitrectomy combined with silicone oil filling operation of rhegmatogenous retinal detachment with retinal de-tachment were randomly divided into two groups,observation group （ n = 40） in postoperative 1 d injection of compound anisodine, continuous injection of 2 weeks, and measurement of 1 d, 14 d after retinal microcircu-lation parameters （ including （ Volume） , （ Flow） , （ Velocity） , and the control group （ n = 40） did not give additional expand blood vessel drugs, measuring time, content and method, and with the observation group. Results：：The Vol, the Flw and the Vel of the control group after 14 d were decreased significantly than that after 1 d treatment （P 〈 0.05）. The Flw and the Vel of the observing group after 14 d are significantly in-creased than that after1 d treatment （ P 〈0.05） . The Vol, Flw, Vel of two groups after 14 d had more signifi-cant difference （ P 〈 0.05） . Conclusion：Compound anisodine for vitrectomy down behind the position of the patient＆#39;s fundus blood circulation has a significant effect,it can reduce secondary retinal ischemia and improve the patient＆#39;s quality of vision, has high clinical value.