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胰岛素自身免疫综合征一例 被引量:1

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摘要 胰岛素自身免疫综合征(insulin autoimmune syndrome, IAS)又称自身免疫性低血糖症(autoimmune hypoglycemia, AIH)[1],是由日本的Hirata等于1970年首次报道,故又称Hirata病。其主要临床特点为反复空腹或餐后晚期的低血糖发作、血胰岛素水平升高、胰岛素自身抗体(IAA)或胰岛素受体抗体阳性[2]。IAS患者比较少见,现报道1例。
作者 石敏
出处 《中国医师进修杂志》 2016年第11期1039-1040,共2页 Chinese Journal of Postgraduates of Medicine
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  • 2Goswami R, Jayasuryan N, Jaleel A, et al. Insulin autoantibodies before and after carbimazole therapy in Asian Indian patients with Graves' disease. Diabetes Res Clin Pract, 1998,40:201-206.
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  • 7Murakami M,Mizuide M, Kashima K, et al. Identification of monoclonal insulin autoantibodies in insulin autoimmune syndrome associated with HLA-DRB1*0401. Horm Res,2000,54:49-52.
  • 8Uehigata Y, Hirata Y, Omori Y, et al. Worldwide differences in the incidence of insulin autoimmune syndrome ( Hiram disease) with respect to the evolution of HLA-DR4 alleles. Hum Immunol,2000,61 : 154-157.
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