摘要
补体系统是免疫系统的重要组成部分,参与病原物的识别和防御,是机体抵抗致病性感染的第一道防线。补体途径通过经典途径、凝集素途径和替代途径3条途径激活,在宿主免疫及多种生理、病理过程中发挥重要作用。本文对补体激活与肝炎病毒复制相关性的研究现状作一综述。
Complement system is an important part of immune system, which participates in the recognition and defense of pathogen and is served as the first line of defense against pathogenic infection. After being activated by the classical pathway, lectin pathway and alternative pathway, complement selectively recognizes foreign pathogens and damaged self-cells, which plays an important role in the host immune and a variety of physiogical and pathological processes. This paper reviews the research progress of relationship of complement activation to replication of hepatitis virus.
出处
《中国生物制品学杂志》
CAS
CSCD
2016年第11期1225-1228,共4页
Chinese Journal of Biologicals
基金
国家自然科学基金项目(31360619
81660338)
云南省自然科学基金项目(2013FB032
2011FZ068)
中国博士后科学基金项目(2014M562672)
关键词
补体
病毒性肝炎
攻膜复合物
自身免疫性肝炎
Complement
Viral hepatitis
Membrane attack complex
Autoimmune hepatitis