外阴浅表性基底细胞癌1例

A Case of Superficial Basal Cell Carcinoma on the Vulva

患者女,76岁。右侧大阴唇暗红斑6年,黑色丘疹伴灼痛1年。皮肤科情况:右侧大阴唇散在分布较多针尖至粟粒大黑色丘疹,其下方见一约2cm×1cm大暗红色斑片,形状不规则,界清,暗红斑上见多发针尖至粟粒大小黑色丘疹,融合成片,边缘呈线状隆起,表面可见点状糜烂、浅溃疡。皮损组织病理示:表皮轻度萎缩;真皮浅层见由基底样细胞构成的瘤团,瘤细胞团自表皮底部呈芽蕾状或不规则生长至真皮乳头层,瘤体多处与表皮相连,真皮浅层淋巴细胞呈带状浸润;真皮深层未见异常。诊断:浅表性基底细胞癌。

A 76-year-old female presented with dark red patch on the right vulva for six years, and black papules with burning pain for one year. Physical examination revealed many black papules sized from needle-point to millet scattered on the right vulva. There was a well-demarcated and irregularly shaped dark red patch sized about 2cm ×1cm with a elevated linear border. Some papules merged together to form dark red patch with punctate erosion and superficial ulcers. Histopathology of skin lesion showed mild epidermal atrophy. The tumor masses were consisted of many basaloid cells in the upper dermis. The tumor displayed bud-like or irregular growth, extending from epidermal basal layer to the dermal papilla layer. Multiple connection points between tumor and the epidermis could be seen. Band-like infiltration of lymphocytes presented in the Upper dermis. The lower dermis appeared normal. Diagnosis： Superficial basal cell carcinoma.