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对冠心病患者进行血清NT-ProBNP检测在诊断其病情及评估其预后中的临床价值 被引量:2

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摘要 目的 :探讨对冠心病患者进行血清氨基末端B型钠尿肽原(NT-ProBNP)检测在诊断其病情及评估其预后中的临床价值。方法 :将近年来我院收治的60例冠心病患者及在我院进行体检的60例健康人作为研究对象,将60例冠心病患者纳入冠心病组,将60例健康人纳入健康组,对两组受试者进行血清NT-ProBNP水平的检测,然后对比分析两组受试者血清NT-P ro BNP的水平及冠心病组患者在接受治疗后的第7天、第15天、第30天其血清NT-ProBNP水平的变化情况。结果:与健康组受试者相比,冠心病组患者血清NT-ProBNP的水平较高,差异有统计学意义(P<0.05)。随着冠心病组患者病情的加重,其血清NT-ProBNP的水平逐渐升高。在进行治疗前,冠心病组中无自觉症状的患者其血清NT-ProBNP的水平低于稳定性心绞痛患者,稳定性心绞痛患者血清NT-ProBNP的水平低于不稳定性心绞痛患者,不稳定性心绞痛患者其血清NT-ProBNP的水平低于急性心肌梗死患者,差异均有统计学意义(P<0.05)。随着治疗时间的延长,冠心病组中不同病情的患者血清NT-ProBNP的水平均逐渐降低。冠心病组中不同病情的患者在进行治疗前其血清NT-ProBNP的水平均高于进行治疗后的第7天,进行治疗后的第7天其血清NT-ProBNP的水平均高于进行治疗后的第15天,进行治疗后的第15天其血清NT-ProBNP的水平均高于进行治疗后的第30天,差异均有统计学意义(P<0.05)。结论 :冠心病患者血清NT-ProBNP的水平与其病情的严重程度有密切的关系。对冠心病患者进行血清NT-ProBNP检测,对于在早期诊断其病情及判定其预后具有重要的临床价值。
作者 周祁云
出处 《当代医药论丛》 2016年第20期65-67,共3页
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