内镜逆行胰胆管造影治疗胆总管结石1942例临床分析

A clinical analysis of 1942 cases with common bile duct stones treated with endoscopic retrograde cholangiopancreatography

目的总结内镜逆行胰胆管造影（ERCP）治疗胆总管结石的临床特点。方法回顾性分析1942例行ERCP治疗胆总管结石的的临床资料，分为青年组（18-44岁）、中年组（45～64岁）和老年组（≥65岁），分层分析三组患者性别、基础疾病、取石结果以及术后并发症发生情况。结果基础疾病患病率随年龄增加而升高（P〈O．01），取石成功率随年龄增加而降低（P〈O．01）。老年组结石大小和胆总管直径大于青年组和中年组（P〈O．05）；而三组患者性别、结石数目、合并乳头旁憩室及术后并发症无统计学差异（P〉O．05）。结论ERCP治疗不同年龄层患者胆总管结石均是有效而安全的。

Objective To summarize the clinical characteristics of endoscopic retrograde cholangiopancreatography（ERCP） in treating common bile duct stones. Methods The data of 1942 patients with common bile duct stones treated with ERCP were retrospectively analyzed, who were assigned into three groups of A（18-44 years old）, B（45-64 years old） and C（≥65 years old）. A stratification analysis of the gender, underlying diseases, stone removal results and postoperative complications were performed. Results As the age increased, the prevalence rate of comorbidities was elevated,while success rate of stone removal was decreased（P〈0. 05）. The stone size and diameter of common bile duct were larger in group C than those in groups of A and B（P〈O. 01）. There were no significant differences in the gender, stone number, combination with peripapillary diverticulum and postoperative complications among three groups（P〉0. 05）. Conclusion The ERCP in the treatment of common bile duct stones is effective and safe in the Datients with different ages.