J Clin Pharm Ther：外用聚维酮碘溶液能够导致血糖测量值高估

Probable glucometer interference caused by topical iodine solution test site preparation

血液中的糖分称为血糖，绝大多数情况下都是葡萄糖（英文简写Glu）。体内各组织细胞活动所需的能量大部分来自葡萄糖，所以血糖必须保持一定的水平才能维持体内各器官和组织的需要。根据一项病例报告，使用外用碘溶液能够导致血糖测量值高估。相关研究结果在线发表在Journal of Clinincal Pharmacy and Therapeutics期刊上。论文标题为＂Probable glucometer interference caused by topical iodine solution test site preparation＂。

Use of disinfectants, such as alcohol prep pads, for test site preparation have demonstrated alterations in glucose readings. One case report details an overestimation of blood glucose (BG) readings when using Chemstrip bG and Visidex reagent test strips after cleaning test site with povidone-iodine swabsCase SummaryWe present a case of a clinically relevant probable drug-device interaction between topical iodine and a point-of-care glucometer in a 28 year old pregnant woman of Chinese descent. In this case, the use of 10% povidone-iodine solution on the testing site before lancing likely resulted in variable and inaccurate BG readings, which was not reproduced when the patient used hand washing instead of iodine.What is new and ConclusionOur report expands on this prior knowledge by demonstrating that such an alteration associated with iodine can occur with modern electrochemical glucometers. In patients that have aberrant or variable BG readings, providers should investigate for improper testing technique.