引导再生术用于下颌第三磨牙拔除后牙槽骨再生的疗效评估

Curative effect evaluation of GBR on alveolar bone regeneration after impacted mandibular third molar extraction

目的观察联合应用Bio-oss骨代材料和Bio-gide胶原膜的引导骨再生术(guided bone regeneration,GBR)治疗下颌阻生第三磨牙拔除后邻牙远中牙槽骨缺损的疗效。方法将24例下颌阻生第三磨牙拔除患者随机分为GBR组和对照组,GBR组12例,对照组12例。GBR组拔牙后行Bio-oss、Bio-gide引导骨再生术。对照组拔牙后常规处理拔牙创。分别记录术前、术后3个月拔牙区域牙槽骨再生情况,邻牙远中牙周探诊深度(probing depth,PD)、牙槽嵴顶到釉牙骨质界的距离、松动度及敏感度。结果与术前相比两组术后拔牙区域均存在牙槽骨再生,X线片显示,GBR组疗效优于对照组,且有显著性差异。GBR组新骨形成量较多,牙周探诊深度减小,邻牙远中牙槽嵴顶到釉牙骨质界的距离减小。无邻牙松动和敏感病例,对照组新骨形成量较少,牙周探诊深度和邻牙远中牙槽嵴顶到釉牙骨质界的距离变化不明显,存在部分邻牙松动和敏感病例。结论联合应用Bio-oss骨代材料和Bio-gide胶原膜行引导骨再生术可促进拔牙区域牙槽骨再生和邻牙远中牙槽骨高度的改善。

Objective To observe the effects of combined use of Bio-oss bone collagen membrane and Bio-gide generation materials of guided bone regeneration in the treatment of mandibular third molar alveolar bone defect after extraction. Methods 24 cases of mandibular third molar patients with tooth extraction were randomly divided into GBR group and control group,each group having 12 patients. GBR group received scratch,alveolar bone repair,Bio-oss and Bio- gide GBR techniques after extraction; control group only received scratch and alveolar bone repair. The conditions of alveolar bone regeneration of all patients were recorded after 3 months. Results Both two groups had alveolar bone regeneration compared with the preoperative. X-ray showed,GBR group was better than the control group,and had significant differences. New bone formation and adjacent teeth of alveolar bone height of GTR group was better than control group. Conclusion Combined use of Bio-oss bone collagen membrane and Bio-gide generation materials of guided bone regeneration promotes alveolar bone regeneration of tooth extraction area and improves alveolar bone height of adjacent teeth.