摘要
目的:探讨西咪替丁联合喜炎平对病毒性肠炎患儿炎性因子的影响。方法:选取在医院进行治疗病毒性肠炎患儿106例,随机分为两组,每组各53例。对照组实施西咪替丁治疗,研究组采用西咪替丁联合喜炎平治疗,对比两组临床疗效、相关指标及炎性因子水平。结果:研究组临床疗效明显优于对照组,差异有统计学意义(P<0.05);研究组症状消失时间和住院时间较对照组明显缩短,差异有统计学意义(P<0.05);治疗后研究组肿瘤坏死因子(TNF-α)、白细胞介素10(IL-10)、白细胞介素6(IL-6)水平较对照组明显降低,差异有统计学意义(P<0.05)。结论:对病毒性肠炎患儿实施西咪替丁联合喜炎平治疗具有较好的临床疗效,可改善患儿临床症状,降低患儿炎性因子水平。
Objective:To analyze the effects of cimetidine combined with Xiyanping on inflammatory factors of children with viral enteritis.Methods:106children with viral enteritis in Maternal and Child Health Care Centre of Jishui County had been randomly divided into two groups,53 cases in each.Cimetidine had been used in the control group,cimetidine combined with Xiyanping in the study group,and two groups had been compared in terms of clinical curative effects,the related indexes and inflammatory factor levels.Results:The clinical efficacy of the study group was significantly better than the control group and the difference was significant(P<0.05);the time of symptoms disappearance and the hospital time were significantly shorter than the control group and the differences were significant(P <0.05);the tumor necrosis factor,alpha(TNF-alpha),interleukin 10(IL-10)and interleukin 6(IL-6)levels in the study group after the treatment were significantly lower than the control group,the differences being significant(P<0.05).Conclusion:Cimetidine combined with Xiyanping has good clinical efficacy in treatment of children with viral enteritis,which can lessen clinical symptoms and reduce the level of inflammatory factors in the children.
