肺部肿瘤化疗对癌症患者耐甲氧西林金黄色葡萄球菌(MRSA)的影响

Lung cancer chemotherapy impact on cancer patients with methicillin-resistant Staphylococcus aureus(MRSA)

目的:研究癌症患者肺部肿瘤化疗后耐甲氧西林金黄色葡萄球菌(MRSA)变化情况。方法:回顾性分析100例肺部肿瘤化疗患者的MRSA感染资料。从感染者鼻、喉和其他感染部位获得MRSA定植拭子,进行生物检验。结果:44例患者为MRSA携带者。MRSA败血症48例,其中42%的患者中性粒细胞计数<500/μl。MRSA致命并发症仅8例。MRSA败血病死率为14.6%。结论:化疗抗肿瘤可用于MRSA感染的肺癌患者,并且不必减少剂量或延迟治疗。

Objective ：To study the lung cancer chemotherapy for cancer patients methicillin-resistant Staphylococcus aureus （MRSA） .Methods ：We retrospectively analyzed the clinical data of 100 cases of lung cancer chemotherapy were MRSA-infected patients .Results ：44 patients were colonized with MRSA ,and 56 patients colonized and / or infected with MRSA .48 cases of MRSA sepsis .In addition ,during MRSA sepsis ,42% of patients with neutrophil count 〈 500/μl .However ,MRSA only 8cases of fatal complications .MRSA sepsis-induced mortality rate was 14 .6% .Conclusion ：The anti-tumor chemotherapy may be administered to a patient with lung cancer MRSA infection ,and does not necessarily reduce the dose or delay treatment .