免疫调节治疗对肺结核患者细胞免疫功能的影响研究

Effect research of immune regulation therapy on the cellular immune function in patients with pulmonary tuberculosis

目的:探讨免疫调节治疗对肺结核患者细胞免疫功能的影响。方法:收治肺结核患者60例,随机分为两组。对照组给予常规抗结核治疗,观察组在对照组基础上给予免疫调节治疗,比较两组IL-2和IFN-γ水平及T细胞增殖情况。结果:观察组治疗后IL-2、IFN-γ均高于对照组,差异具有统计学意义(P<0.05)。观察组T细胞增殖能力、免疫功能均优于对照组,差异具有统计学意义(P<0.05)。结论:免疫调节治疗能提高肺结核患者的细胞免疫功能。

ObjectiveTo investigate the effect of immune regulation on the cellular immune function in patients with pulmonarytuberculosis.Methods：60 cases of patients with pulmonary tuberculosis were divided into two groups randomly.The control groupwas given conventional anti-tuberculosis treatment.The observation group was given immune regulation treatment based on thecontrol group.The levels of IL-2 and IFN-γ and proliferation of T cells in the two groups were compared.Results：The levels ofIL-2 and IFN-γ in the observation group after treatment were higher than those in the control group,and the differences werestatistically significant （P〈0.05）.The proliferation ability of T cells and immune function in the observation group were betterthan those in the control group,and the differences were statistically significant （P〈0.05）.Conclusion：Immune regulation therapycould improve the cellular immune function of patients with pulmonary tuberculosis.