期刊文献+

地特胰岛素联合二甲双胍治疗2型糖尿病的临床疗效观察 被引量:1

下载PDF
导出
摘要 目的:观察地特胰岛素联合二甲双胍治疗2型糖尿病的临床疗效。方法:选取我院就诊的100例2型糖尿病患者,随机分为观察组(地特胰岛素+二甲双胍)和对照组(地特胰岛素)各50例。对比两组临床疗效。结果:观察组总有效率92.00%显著高于对照组80.00%(P<0.05)。两组治疗前FBG、2hPG、HbA1c水平和胰岛素用量比较无差异(P>0.05)。治疗后观察组FBG、2hPG、HbA1c水平和胰岛素用量显著低于治疗前(P<0.05);对照组FBG、2hPG和HbA1c水平显著低于治疗前(P<0.05);胰岛素用量与治疗前比较,差异无统计学意义(P>0.05)。观察组FBG、2hPG、HbA1c水平和胰岛素用量显著低于对照组(P<0.05)。结论:2型糖尿病患者使用地特胰岛素联合二甲双胍治疗,临床效果显著,减少药物使用剂量,值得临床推广。
作者 李艳芳
出处 《中外女性健康研究》 2016年第17期199-199,230,共2页 Women's Health Research
  • 相关文献

参考文献4

二级参考文献55

  • 1陈家伦.新一代治疗糖尿病的药物──阿卡波糖[J].中华内分泌代谢杂志,1995,11(3):170-173. 被引量:53
  • 2单洁,栾向萍,丁秀芳,金立.甘精胰岛素联合阿卡波糖治疗2型糖尿病的疗效观察[J].中国医师进修杂志(内科版),2007,30(6):55-56. 被引量:24
  • 3Hermansen K, Davies M, Derezinski T. A 26-week randomized, parallel,treat-to-target trial comparing insulin detmnir with NPH insulin as add-on therapy to oral glucose-lowering druge in insulin- naive people with type 2 diabetes [ J ]. Diabetes Care, 2006,29 (6) :1269-1274.
  • 4Rosenstock J, Davies M, Home P D. A randomized,52-week, treat- to-target trial comparing insulin detemir with insulin glargine when administered as add-on to glucose-lowering drugs in insulin-naive people with type 2 diabetes [ J ]. Diabetologia, 2008,51 ( 3 ) : 408- 416.
  • 5Hordem S V,Wright J E, Umpteby A M. Comparison of the effects on glucose and lipid metabolism of equipotent doses of insulin det- emir and NPH insulin with a 16-h euglycaemic clamp[J]. Diabeto- logia ,2005,48 ( 3 ) :420-426.
  • 6Klein O. Albumin-bound basal insulin analogues ( insulin detemir and NN344) : comparable time-action profile but less variability than insulin glargine in type 2 diabetes[J].Diabetes Obes Metab, 2007,9 ( 3 ) :290-299.
  • 7Heise T. Lower within-subject variability of insulin detemir in com- parison to NPH insulin and insulin glargine in people with type 1 diabetes[J]. Diabetes ,2004,53 ( 6 ) : 1614-1620.
  • 8Bohm A ,Staiger H, Hennige A M. Effect of insulin detemir, cornpared on hunmn insulin, on 3T3-L, adipogenesis [ J ]. Regul tYpt, 2008,151(1/3) :160-163.
  • 9Domhorst A,Ltiddeke H J, Koenen C. Transferring to insulin det- emir from NPt4 insulin or irtsulin glargine in type 2 diabetes pa- tients on basal-only therapy with oral atttidiabetic drugs improves glycaemic control and reduces weight gain and risk of hypoglycae- mia : 14-week follow-up data from PREDICTIVE[J].Diabetes Obes Metab ,2008,10( 1 ) :75-81.
  • 10Weng J,Li Y,Xu W,et al.Effect of intensive insulin therapy on beta cell function and glycaemic control in patients with newly diagnosed type 2 diabetes : a multicentre randomised parallel -group trial [ J ]. Lancet, 2008,371 (9626) : 1753-1760.

共引文献49

同被引文献6

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部