不同年份、不同产地西红花药材的质量研究

Quality Study on Croci Stigma Collected in Different Years and Different Places

目的通过对不同年份、不同产地的西红花药材进行质量分析,评价储藏年份以及产地对药材质量的影响。方法收集不同年份、不同产地的西红花药材,对其进行质量考察,主要包括药材鉴定和含量测定。结果随着储存年份的延长,西红花药材有不同程度的褪色情况,且西红花总苷含量呈降低趋势;比较不同产地的西红花药材,结果发现,建德、上海产的西红花药材西红花总苷含量>10%,国外的西红花药材部分批次没有达到药典要求。结论随着保存年份的增加,西红花药材的外观性状以及西红花苷含量会有较大改变,采取特殊的保存措施能抑制其含量的降低;且不同产地的西红花药材中西红花苷含量也不同,国产药材西红花苷含量较高,可能与加工和保存方法有关。

OBJECTIVE To evaluate the influence of the storage year and places of origin on the quality of medicinal materials through the quality analysis for the Croci Stigma of different years and different places. METHODS The Croci Stigma of different years and different places were collected to study the quality inspection, mainly including the identification and content determination of medicinal herbs. RESULTS As the extension of storage year, the Croci Stigma had faded in different degrees, and the total glycosides content of Croci Stigma showed a trend of decrease; Compared the Croci Stigma of different regions, the results showed that the total glycosides content of Croci Stigma made in Shanghai and Jiande were 10%, some batches of Croci Stigma abroad didn＇t reach the requirements of pharmacopoeia. CONCLUSION As the extension of storage year, the appearance of the Croci Stigma and the content of total glycosides in Croci Stigma will be a big change, while taking some special preservation measures can inhibit the decrease of its content; and the Croci Stigma glycosides content in different places are also different, domestic medicinal materials have higher glycosidescontent of Croci Stigma, which may be related to the processing and preservation methods.