正交设计法用于妇洁灵洗剂的提取工艺研究

Research of Extraction Technology of Fujieling Lotion by Orthogonal Design

目的：优选妇洁灵洗剂主要有效成分提取工艺。方法：以该复方主要成分苦参碱的转移率为指标,选取3个考察因素（加水量、提取时间和次数）,采用L_9（3-4）正交表进行优选提取工艺实验。结果：提取工艺中10倍量水加热回流提取2次,每次2h为最优工艺。结论：妇洁灵洗剂经正交试验优选的提取工艺可行。

Objective：To optimize extraction technology of main effective components of Fujieling lotion.Methods：3factors（amount of water,extraction time and number of extractions）were selected by using L_9（3-4）orthogonal table to optimize the extraction technology,which were indexed by transfer rate of matrine.Results：10times the amount of water,2times heating reflux extraction and each time for 2hours was the optimal process.Conclusion：Extraction technology of Fujieling lotion through orthogonal test optimization is feasible.