20%氯胺嘧草醚悬浮剂的高效液相色谱分析

Analysis of ZJ1835 20% SC by HPLC

【目的】建立高效液相色谱法测定20％氯胺嘧草醚悬浮剂中有效成分的分析方法。【方法】使用Acclaim C18色谱柱，以乙腈和水作为流动相（体积比80：20），检测波长为245nm，对氯胺嘧草醚进行定量分析。【结果】当氯胺嘧草醚的质量浓度为11．7～468mg／L时，该方法的线性相关系数为1．0000，相对标准偏差为0．11％，平均回收率为99．09％。【结论】该方法具有较宽的线性范围，准确度、精密度好，操作方便，可以用作氯胺嘧草醚悬浮剂的定量分析。

[Aims] The HPLC method for determination of ZJ1835 20% SC was established. [Methods] The sample was analyzed with Acclaim C18 column, and with the mixture soultion of acetonitrile and water as mobile phase （80：20, by vol） at 245 nm. [Results] When the concentration of ZJ1835 was between 11.7 and 468 mg/L, the linear correlation coefficient of the method was 1.0000, the relative standard deviation was 0.11%, and the recovery rate was 99.09%. [Conclusions] The described method has a wide linear range, high precision and accuracy, and easy to operate, which can be used in determination of Z J1835 suspension concentrate.