增殖性脑血管病致脑梗死一例报道并文献复习

Cerebral Infarction Caused by Cerebral Proliferative Angiopathy: A Case Report and Literature Review

动脉粥样硬化后脑血管管腔狭窄乃至闭塞是脑梗死最常见原因,本文报道1例增殖性脑血管病(CPA)致脑梗死患者,患者脑梗死区域血管较正常脑组织丰富。通过文献复习,对CPA患者的临床表现、影像学表现、血管造影、病理、发病机制、治疗和预后进行讨论。目前,文献报道CPA致脑梗死病例较少,颅脑CT血管成像可见病灶区血管异常丰富,应根据患者具体情况制定个体化治疗方式,预后尚难以评估。

Atherosclerosis,which resulted in cerebral vascular stenosis or even occlusion,is the most common cause of cerebral infarction. Here we reported a case of cerebral infarction caused by cerebral proliferative angiopathy（ CPA）. There were more blood vessels in cerebral infarction area than normal brain tissue in the patient. Through the literature review,we discussed clinical manifestations,imaging and digital subtraction angiography appearances,pathological features,pathogenesis,treatment,and prognosis of CPA. Only few cases of cerebral infarction caused by CPA have been described in the world literature till now. CT angiography imaging could demonstrate unusually abundant blood vessels in the lesion. Treatment should be adapted to the patient specific characteristics,while the prognosis of CPA is hard to predict.