慢性胆囊炎患者电针针刺阳陵泉穴后胆囊收缩素变化与胆囊动脉血流动力学观察

Effects of Electroacupuncturing at Yanglingquan on Cholecystokinin Change and Arterial Hemodynamics of Gallbladder in Patients with Chronic Cholecystitis

目的探讨慢性胆囊炎患者电针针刺阳陵泉穴对胆囊收缩素水平和胆囊动脉血流动力学的影响。方法选取2012年12月—2014年6月于聊城市第二人民医院就诊的慢性胆囊炎患者40例为研究对象,采用随机数字表法将患者分为试验组和对照组各20例。试验组电针针刺阳陵泉穴,进针得气后连接电针仪,选用连续波,频率60 Hz,刺激强度以患者局部有明显跳动但不过分强烈为度,留针30 min后关机出针。对照组以同样方法电针针刺同侧足三里穴和阳陵泉穴连线中点下方1.5 cm处假穴。于针刺穴位前10 min及针刺后30 min抽取静脉血,采用放射免疫法检测胆囊收缩素水平;采用彩色多普勒超声诊断仪检测胆囊动脉血流动力学指标,包括最大血流速度(Vmax)、最小血流速度(Vmin)、阻力指数(RI)。结果两组电针针刺前胆囊收缩素水平比较,差异无统计学意义(P>0.05)。试验组电针针刺后胆囊收缩素水平高于对照组(P<0.05)。试验组电针针刺后胆囊收缩素水平高于电针针刺前(P<0.05)。两组电针针刺前Vmax、Vmin、RI比较,差异无统计学意义(P>0.05)。试验组电针针刺后Vmax、Vmin低于对照组,RI高于对照组(P<0.05)。试验组电针针刺后Vmax、Vmin低于电针针刺前,RI高于电针针刺前(P<0.05)。结论电针针刺阳陵泉穴可促进慢性胆囊炎患者胆囊收缩素分泌,胆囊动脉血流速度减慢,RI增加。

Objective To explore the effects of electroacupuncturing at Yanglingquan on the level of cholec：ys＇to＇kinin and arterial hemodynamics of gallbladder in patients with chronic cholecystitis. Methods We enrolled 40 chronic cholecystitis patients who were admitted into the Second People＇s Hospital of Liaocheng from December 2012 to June 2014. We divided the patients into experimental group and control group, with 20 patients in each group. The experimental group were electroacupunctured at Yanglingquan, and connected with electricacupuncture after insertion of needle and the qi sensation, selected continuous wave with 60 Hz. The stimulation intensity degree was that patients had partial obvious beating but not too strong. The needle was retained for 30 min, then electric acupuncture was turned off and the needle was withdrawn. The control group were electroacupunctured at the points 1.5 cm below the midpoint of the line segment of lateral to the acnpoints of Zusanli and Yanglingquan at the same foot side. The level of cholecystokinin was detected by radio ty at 10 min before and 30 min after electroacupuncturing. Vmax, Vmin, RI of gallbladder artery hemodynamics were measured with color Doppler ultrasound imaging at the same time. Results The comparison of the level of cholecystokinin between two groups before electroacupuncturing showed the difference was not statistically significant （P 〉0. 05 ） . After acupuncture, the level of cholecystokinin in the experimental group was significantly higher than that in the control group （ P 〈 0.05 ） . In the experimental group, the level of cholecystokinin after electroacupuncturing was significantly higher than before （ P 〈 0. 05 ） . Vmax, Vmin and RI of gallbladder artery of the two groups showed that the difference was not statistically in before electroacupuncturing （ P 〉 0. 05 ） . After electroacupuncturing, Vmax, Vmin of gallbladder artery of the experimental group were significantly lower while and RI was significantly higher than those of control group （ P 〈 0.05 ） . In the experimental group, Vmax, Vmin of gallbladder artery were also significantly lower and RI higher after electroacupuncturing than before （ P 〈 0. 05 ） . Conclusion Eleetroacupuneturing Yanglingquan can increase promote the level secretion of cholecystokinin of patients with chronic cholecystitis, promote gallbladder emptying, decrease blood flow velocity of gallbladder artery and increase RI.