羟考酮用于饱胃流产患者镇痛效果的临床观察

Clinical Observation on Oxycodone for Full Stomach Abortion Analgesia

目的观察羟考酮用于饱胃流产患者的镇痛效果。方法选择门诊行无痛人流的饱胃患者40例,ASAⅠ或Ⅱ级,年龄18~40岁,体重49~70kg,孕周5~10周。随机分为羟考酮组和对照组。羟考酮组患者入室后给予羟考酮0.1mg/kg静注,对照组患者静脉给予生理盐水0.1mg/kg。5min后手术医生消毒、铺巾,手术开始。记录患者入室后（T1）、牵拉宫颈时（T2）、手术结束后（T3）患者的VAS评分,记录患者术中呼吸循环情况和术后恶心呕吐等不良反应情况。结果羟考酮组患者在T2,T3时VAS评分明显低于对照组（P〈0.05）,并且无明显呼吸抑制及恶心呕吐发生。结论对于饱胃要求行流产手术的患者应用羟考酮在保证安全性同时可提供良好镇痛。

Objective To observe the analgesic effect of oxycodone for full stomach abortion patients. Methods Forty full stom- ach pregnant patients, aged 18 -40, weighing 49 -70kg, ASA I or II , were randomly divided into two groups. Each group had 20 cases. When entered room,oxyeodone group were given oxycodone 0.1 mg/kg,while control group were given physiological salt 0.1 mg/kg by intravenous injection. After 5 min surgery doctor began to disinfection and spread towels,operation strated. Record patients ernter room（ T1 ） , stretch the cervix （ T2 ） after the surgery （ T3 ） with VAS score, the adverse reactions such as respiratory cycle and postoperative nausea and vomiting were also recorded. Results Oxyeodone group in T2, T3, VAS score significantly lower than the control group （ P 〈 0.05 ） , and no obvious respira- tory depression and nausea and vomiting. Conclusion For the full stomach abortion patients application of oxycodone in security at the same time can provide good analgesia.