透明质酸钠联合人工周期疗法治疗宫腔粘连分离术后66例的临床疗效观察

The clinical efficacy of sodium hyaluronate combined with artificial cycle therapy in treatment of 66 cases of uterine cavity adhesion

目的:观察透明质酸钠联合人工周期疗法治疗宫腔粘连分离术后临床效果,以期为术后宫腔粘连的后续治疗以及预防再粘连提供依据。方法:选取因宫腔操作后B超提示见宫腔粘连带,并经宫腔镜检查术证实存在中重度宫腔粘连的住院患者66例,随机分为3组,3组均行宫腔粘连分离术,术后进行不同的治疗方式,其中A组于术后予透明质酸钠联合人工周期疗法,B组术后放置宫内节育器并予人工周期疗法,C组为对空白对照组,术后直接予人工周期疗法,3组均三个月后予宫腔镜复查粘连情况及随访三个月月经改善情况。结果:宫腔粘连改善率及月经改善情况以A组疗效最优。结论:透明质酸钠联合人工周期疗法能够有效预防宫腔黏连分离术后再粘连,以及改善患者月经。

Objective： To observe the clinical effect of sodium hyaluronate combined with artificial cycle therapy in the treatment of uterine cavity adhesion, in order to provide evidence for further treatment and prevention of postoperative adhesion. Methods： Patients with uterine cavity operation after b-tip see intrauterine adhesions, and after hysteroscopy confirmed the presence of severe intrauterine adhesions in 66 cases, were randomly divided into 3 groups, 3 groups were intrauterine adhesions, after different treatment, which in group A were treated by sodium hyaluronate combined with artificial cycle therapy, B group after IUD and treated with artificial cycle therapy, C group of blank control group, postoperative with artificial cycle therapy, 3 groups were treated after three months and follow-up hysteroscopy revealed adhesion three months of menstruation. Results： the improvement rate of intrauterine adhesion and the improvement of menstruation in the treatment of a group were the best. Conclusion： sodium hyaluronate combined with artificial cycle therapy can effectively prevent the adhesion of uterine cavity adhesion, and improve the patient＇s menstruation.