中西医结合治疗中老年睑板腺功能障碍导致的干眼症的疗效评价

THE CURATIVE EFFECT OF COMBINED TREATMENT OF CHINESE AND WESTERN MEDICINE ON XEROPHTHALMIA INDUCED BY MEIBOMIAN GLAND DYSFUNCTION

目的:观察中西医结合治疗中老年睑板腺功能障碍(MGD)导致的干眼症的临床疗效。方法:将80例(160眼)MGD导致的干眼症患者随机分为治疗组和对照组,每组40例(80眼),治疗组给予中西医结合的药物治疗、局部物理治疗等综合治疗,对照组仅给予西药治疗和局部物理治疗等,不包括中药治疗,疗程为3个月。对两组患者结膜充血情况、泪河宽度,泪膜破裂时间(BUT)及Schirmer I等各项指标进行比较分析。结果:治疗组和对照组治疗后球结膜充血情况、泪河宽度和BUT及Schirmer I结果均较治疗前改善,差异均有统计学意义(均P<0.05)。治疗组患者的临床疗效优于对照组,差异具有统计学意义(P<0.05)。结论:中西医结合的综合治疗方法能够更好地治疗患者疾病,改善患者各项检测指标,缓解患者眼部的不适症状。

Objective：To study the curative effect of combined treatment of Chinese and Western medicine on xerophthalmia of middle-age and eldly patients which induced by meibomian gland dysfunction（MGD）.Methods：80patients（160eyes）with dry eyes induced by MGD were randomly divided into the treatment group and the control group.The treatment group was given comprehensive treatment,including traditional Chinese medicine combined with western medicine treatment,and local and physical therapy.The control group was given only western medicine treatment,local and physical therapy,not including the traditional Chinese medicine treatment.The treatment period lasted for 3 months.The clinical effects of treatments were evaluated.Results：The corneal epithelial shedding,conjunctival congestion,tear river width,tear film break-up time（BUT）and Schirmer I of the two groups were improved after treatment（P〈0.05）.The clinical curative effect of the treatment group were better than those of the control group（Z=3.98,P〈0.05）.Conclusion：The comprehensive treatment including TCM can achieve better curative effect on xerophthalmia,and alleviate the ocular discomfort symptom of patients.