新型人感染H7N9型禽流感病毒研究进展

The progress of the novel human infected H7N9 avain influenza viruses

人感染新型H7N9型禽流感自2013年确诊以来全国蔓延,表现出极高的致病率及致死率,引发了极大的关注。该病由新型H7N9型禽流感病毒引起,该病毒基因突变率高,一旦发生对人类呼吸道上皮受体的适应性突变,极易导致暴发性大流行。文中从H7N9型禽流感的流行病学特征、病原学特征、感染患者的特征、检测措施及防治策略等方面对目前的研究进展进行综述。

Chinese Center for Disease Control and Prevention published three confirmed novel H7N9 avain influenza virus infection cases on March 31,2013.The disease then spread across China and caused extremely high morbility and mortality,which triggered extensive attention.These cases were caused by a novel H7N9 avian influenza virus which was highly mutable.Once the virus adapted to human respiratory epithelium receptors,a pandemic outbreak would occur immediately.This article summerizes the research progress on the H7N9 avain influenza,including epidemiologic characteristics,etiology features,clinical manifestation,detection techniques as well as theraputic and prevention strategy.