某院2015年中成药合理使用的相关因素分析

Analysis of Revevant Factors of Clinical Usage of Chinese Patent Medicine in A Hospital durin 2015

目的:分析2015年中成药使用情况,为临床合理使用提供参考。方法:从门急诊777 242张处方中随机抽取493张,分析门急诊处方中成药的合理使用情况,分析2015年全院中成药相关性药物不良反应(Adverse drug reaction,ADR)。结果:抽取的493张门急诊处方中,开具中成药的处方为239张占48.48%,中成药处方中口服制剂占69.00%,静脉用药占27.6%;不合理处方总数为76张,其中中成药使用不合理处方占不合理处方总数15%;2015年医院ADR为190例,其中中成药相关性ADR占9.47%,与抗菌药物联合使用的占7.89%。结论:医院临床中成药尤其是中药注射剂的使用比例较高,致ADRs的发生率上升,应加强对中成药使用的行政干预,确保患儿用药安全有效。

Objective： To analyze the use of Chinese patent medicine in our hospital and to provide the reference of clinical reasonable usage of these drugs. Methods： 493 prescriptions were collected randomly from 777 242 prescrip- tions of our hospital in 2015 and the usage and adverse drug reactions of Chinese patant medicine were analysed. Re- sults： Among 48.48% of the collected prescriptions for Chinese patent medicine, the proportions of oral and intravenous medication of these Chinese patent medicine were 69.00% and 27.60%. There were 76 unreasonable prescriptions in the collected prescriptions and the unreasonable prescriptions for Chinese patent medicine accounted for 15%. The number of adverse drug reactions was 190 in 2015, the proportion of Chinese patent medicine related ADR was 9.47% and the ADR related with combination of Chinese patent medicine and antimicrobial drugs accounted for 7.89%. Conclusion： Chinese patent medicines were widely used in our hospital, especially for traditional Chinese medicine injection, which often resulted in ADRs. The administrative intervention on the use of Chinese patent medicine should be strengthened to ensure the safety and effectiveness in children.